Results 171 to 180 of about 15,777,155 (294)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Technology-Driven Group Exercise Program Implementation in an Underserved Community: Multimethod Retrospective Evaluation Study. [PDF]

JMIR Rehabil Assist Technol
Neal WN, Malone LA.
europepmc   +1 more source

Sakai Tutorials and User Guide [PDF]

, 2019
Instructional Technology Development Program (ITDP)
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The Healthy Families Bright Futures Program: Open Pilot to Evaluate Acceptability, Appropriateness, and Feasibility of an Online Dating Violence and Alcohol Prevention Program for LGBTQ+ Youth and Their Caregivers. [PDF]

J Aggress Maltreat Trauma
Littleton H, Edwards KM, Kelly MT, Wheeler LA, Mohamed N, Higgins M, Bradshaw J, Zamundu A, Scheer JR.   +8 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Curriculum in Pharmacoepidemiology Training Programs: A Cross-Sectional Study to Assess Educational Needs and Alignment With Core Competencies. [PDF]

Pharmacoepidemiol Drug Saf
Goodin A, Layton D, Chung R, Osborne V, Ejekam C, Li X, Wen X, Filion KB, Lopes LC, Moga DC.   +9 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Beyond Symptom Reduction: A Qualitative Study of Refugees' Experiences of a Trauma-Informed Community-Based Pain Management Program. [PDF]

Eur J Pain
Appiah RP, Mescouto K, Karran EL, Aparnadas A, Phuentsho K, Cardozo B, Moseley GL.   +6 more
europepmc   +1 more source

Amplifications, Fall 2011, Vol. 4, No. 1 [PDF]

, 2011
Program in Audiology and Communication Sciences,
core   +1 more source