Results 51 to 60 of about 10,481,257 (313)
Dérives impactant la pérennisation de la philosophie pour enfants (P4C)
Éducation et SocialisationThe present paper examines the presuppositions that might accompany the current diversified practices of Philosophy for Children (P4C). A double system of tensions is presented on a theoretical level, based on recent literature on the benefits of P4C ...
Emmanuèle Auriac-Slusarczyk +3 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Effects of Skill Lab Programs in Training of Neurosurgery Residents
Iranian Journal of Neurosurgery, 2021 Background and Aim: Nowadays, surgical educations and training experience new problems. Legal issues and patients' rights are a matter of concern in educational hospitals.
Amir Saied Seddighi +6 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The influence of the authorial program on indexes of physical development of overweight senior pupils in mountain schools of the Carpathian region. [PDF]
Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2011 Influence of the authorial program is examined on the indexes of physical development of overweight senior pupils. The changes of separate indexes of physical development of overweight senior pupils that occupied on the authorial program are shown.
Mukutun L.M
doaj
Современные информационные технологии и IT-образование, 2020 A database containing Perl programs, descriptions and a list of keywords for each program was developed. According to these keywords, the user can determine the area of interest which includes the program, he is looking for.
Anna Kulikovskaya +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source