YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
An Empirical Analysis of Global Soybean Supply Potential and China’s Diversified Import Strategies Based on Global Agro-Ecological Zones and Multi-Objective Nonlinear Programming Models [PDF]
Xiaoyu Jiang +4 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Best practices in global health evaluation: Reflections on learning from an independent program analysis in Bihar, India. [PDF]
Mehta KM, Ward VC, Darmstadt GL.
europepmc +1 more source
A Matlab program to develop the mass and energy analysis of control volumes
Jose Garcia Acevedo +2 more
openalex +1 more source
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Binary program tracing and analysis framework by integrating Intel PT and dynamic instrumentation
To address the problem that while dynamic binary instrumentation frameworks are widely used for automated analysis, they face challenges such as performance overhead and usability issues, a hybrid hardware-software framework was proposed for dynamic ...
PAN Jiaye, SHA Letian, LU Jing, XIAO Fu
doaj
Discussion to: Nonelective coronary artery bypass graft outcomes are adversely impacted by Coronavirus disease 2019 infection, but not altered processes of care: A National COVID Cohort Collaborative and National Surgical Quality Improvement Program analysis. [PDF]
europepmc +1 more source

