Results 211 to 220 of about 34,628,233 (409)

SAFE Homes statistical reports, Q4 SFY 2004

open access: yes, 2001
Quarterly; 4/1/2001 to 6/30/2001-; Title from caption (viewed June 8, 2004).; Latest issue consulted: 01/01/2004 to 03/31/2004.; Issued in multiple vols.; Volumes for 4/1/2001 to 6/30/2001-10/1/2001 to 12/31/2001, 10/1/2003 to 12/31/2003- issued by Dept.
SAFE Homes (Program)
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Risk of Systemic Manifestations in Homozygous Carriers of the Transthyretin V142I Variant: A Million Veteran Program Analysis. [PDF]

open access: yesJ Am Heart Assoc
Sideris K   +19 more
europepmc   +1 more source

SAFE Homes statistical reports, Q3 SFY 2004

open access: yes, 2001
Quarterly; 4/1/2001 to 6/30/2001-; Title from caption (viewed June 8, 2004).; Latest issue consulted: 01/01/2004 to 03/31/2004.; Issued in multiple vols.; Volumes for 4/1/2001 to 6/30/2001-10/1/2001 to 12/31/2001, 10/1/2003 to 12/31/2003- issued by Dept.
SAFE Homes (Program)
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

SAFE Homes statistical reports, Q3 SFY 2005

open access: yes, 2001
Quarterly; 4/1/2001 to 6/30/2001-; Title from caption (viewed June 8, 2004).; Latest issue consulted: 01/01/2004 to 03/31/2004.; Issued in multiple vols.; Volumes for 4/1/2001 to 6/30/2001-10/1/2001 to 12/31/2001, 10/1/2003 to 12/31/2003- issued by Dept.
SAFE Homes (Program)
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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