Results 71 to 80 of about 3,385,810 (267)

CROMES v1.0: a flexible CROp Model Emulator Suite for climate impact assessment [PDF]

Geoscientific Model Development
Global gridded crop models (GGCMs) are simulation tools designed for global, spatially explicit estimation of crop productivity and associated externalities. Key areas for their application are climate impact and adaptation studies.
C. Folberth, A. Baklanov, N. Khabarov, T. Oberleitner, J. Balkovič, R. Skalský   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Uncertainty in soil data can outweigh climate impact signals in global crop yield simulations

Nature Communications, 2016
Global gridded crop models are increasingly used to assess climate change impacts on food production. Here, the authors assess crop yield uncertainty associated with soil data input, reporting that soil type strongly influences yield estimates, and may ...
Christian Folberth, Rastislav Skalský, Elena Moltchanova, Juraj Balkovič, Ligia B. Azevedo, Michael Obersteiner, Marijn van der Velde   +6 more
doaj   +1 more source

The effect of community resilience and disaster risk management cycle stages on morbi-mortality following floods: an empirical assessment [PDF]

Natural Hazards and Earth System Sciences
Practice and policy have emphasized the need for building resilience to climate-related events in a further warming world. Scholarship has studied resilience largely in terms of process, latent capacity informing vulnerability, or the outcome of risk ...
R. Guimaraes, R. Mechler, S. Velev, D. Chapagain, D. Chapagain   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Analyzing the use of fact-checking tools in disaster-risk reduction in Europe through the lens of the heuristic-systematic model

Scientific Reports
Journalists, emergency responders, and the general public facing natural and anthropogenic disasters frequently disseminate emergency information via social media.
Nadejda Komendantova, Tahereh Zobeidi, Masoud Yazdanpanah   +2 more
doaj   +1 more source

Understanding the origin of Paris Agreement emission uncertainties

Nature Communications, 2017
The pledges put forward by each country to meet the goals of the Paris Agreement are ambiguous. Rogeljet al. quantify the uncertainty arising from the interpretation of these pledges and find that by 2030 global emissions can vary by −10% to +20% around ...
Joeri Rogelj, Oliver Fricko, Malte Meinshausen, Volker Krey, Johanna J. J. Zilliacus, Keywan Riahi   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source