Results 71 to 80 of about 8,241,327 (286)

Looking Ahead: Envisioning the Future of the Extension Program Development Model

Journal of Human Sciences and Extension, 2015
This article synthesizes key points from this special issue of the Journal of Human Sciences and Extension and provides recommendations for and predictions about the evolution of the Extension Program Development Model.
Ryan J. Gagnon , Barry A. Garst, Nancy Franz   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Career Development Program for Refugee and Migrant Youth [PDF]

, 2006
The Career Guidance for Refugee and Migrant Young People project is an initiative of the South Metropolitan Migrant Resource Centre funded by the Department of Education and Training.
Gallegos, D., Tilbury, F.
core   +1 more source

Evaluation of the Special Education Course Curriculum According to the Opinions of Teacher Candidates: A Qualitative Study

Uluslararası Türk Eğitim Bilimleri Dergisi
Changes are made in education programs from time to time to perform the teaching profession more efficiently. In this context, special education courses have become taught in all teaching branches. Our research is important in that it can be a source for
Celalettin Özden
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Parent-focused group schema coaching program for parents of adolescents with anorexia nervosa: Intervention mapping study

Chronic Diseases Journal
Livilands Resource Centre, NHS Forth Valley Eating Disorders Service, Stirling, UK AND Department of Justice and Society, University of South Australia, Adelaide ...
Fatemeh Seifi, Javad Molazadeh, Abdulaziz Aflakseir, Changiz Rahimi-Taghanaki, Susan Simpson   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Primer Programa Universitario de diplomado virtual y Maestría en Informática Biomédica en el Perú

Revista Peruana de Medicina Experimental y Salud Pública
El entrenamiento en Informática Biomédica es fundamental para enfrentar los desafíos de un mundo globalizado. Sin embargo, el desarrollo de programas de entrenamiento e investigación en posgrado en esta área son escasos en América Latina.
Patricia J García, Miguel S Egoavil, Magaly M Blas, Eduardo Alvarado-Vásquez, Walter H Curioso, Mirko Zimic, Jesus M Castagnetto, Andrés G Lescano, Diego M Lopez, Cesar P Cárcamo   +9 more
doaj  

Design and pilot evaluation of a brief intervention to reduce transphobia and improve attitudes of government officials to address legal gender affirmation needs of transgender people in Peru

Global Health Action
Legal gender affirmation – legal name and gender marker change – is an important health-promoting health determinant for transgender people. In Peru, the state's failure to universally recognize transgender people’s legal identity limits standardized ...
Sari L. Reisner, Amaya Perez-Brumer, Ximena Salazar, Alfonso Silva-Santisteban   +3 more
doaj   +1 more source