Results 111 to 120 of about 4,968,629 (297)
Post Flight Dynamic Analysis Simulation [PDF]
, 1970 Digital six-degrees-of-freedom, open loop Saturn 5 first stage flight evaluation simulation program obtains post flight simulation of the launch vehicle using actual flight data as input. Results are compared with measured data.
Gregory, B. R.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Investigating dimensions of instructor trust using the words of undergraduate STEM students
Frontiers in EducationIntroductionRecent work has shown that student trust in their instructor is a key moderator of STEM student buy-in to evidence-based teaching practices (EBTs), enhancing positive student outcomes such as performance, engagement, and persistence. Although
Kathy Zhang +9 more
doaj +1 more source
Dealing with Stakeholder Values in the Evaluation of Development Programs. A Methodological Framework for Mid Term Evaluation [PDF]
In mid term program evaluations evaluators are often confronted with the double task of retrospectively judging the program's merit and worth while at the same time advising decision makers concerning future adjustments in courses of action.
Vaessen, Jos
core +1 more source
Arts Corps Program Evaluation Report [PDF]
, 2012 Founded in 2000 on the principle that all young people -- not just those with resources -- should have access to quality arts learning opportunities, Arts Corps is now a leading nonprofit arts education organization in Seattle.
Anne Basham, Mary Murray
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Social SciencesThis qualitative research project seeks to examine the obstacles faced by educators who come to the U.S. as refugees. The three participants in this study are from Iraq, Sudan, and Turkey.
Shyla González-Doğan +3 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Skylab medical data evaluation program (SMEDEP) [PDF]
A day-by-day summary of selected data collected during the experiment is presented. The clinical and environmental data are presented in a mission-day format along with a tabulation of biomedical measurements whose values exceed three standard deviations
Hoffler, G. W. +3 more
core +1 more source