Results 111 to 120 of about 4,694,538 (359)

American Airlines LOFT evaluation program [PDF]

open access: yes
The development of a test program to evaluate recurrent training LOFT and a three-legged scenario used for the evaluation are highlighted.
Jensen, D.
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Credentials, Perpetual “Foreignness”, and Feeling out of Place: Three Stories of Resilience from Teachers of Refugee Background

open access: yesSocial Sciences
This qualitative research project seeks to examine the obstacles faced by educators who come to the U.S. as refugees. The three participants in this study are from Iraq, Sudan, and Turkey.
Shyla González-Doğan   +3 more
doaj   +1 more source

Measuring the Quality of Mentor-Youth Relationships: A Tool for Mentoring Programs [PDF]

open access: yes, 2002
Does my program work? This evaluation guide helps program coordinators answer that question by gauging the effectiveness of both individual relationships and the program as a whole through a simple 20-question survey given to youth.
Linda Jucovy
core  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Estimating Impact of a Continuous Program under a Conditional Independence Assumption [PDF]

open access: yes
Traditional literature on impact evaluation often deals with binary programs. In reality, a program can provide different amounts of treatment for people, and it is regarded as a continuous variable. This paper discusses impact evaluation of a continuous
Nguyen Viet, Cuong
core   +1 more source

Evaluation of the Anchorage Coordinated Agency Network (CANS) Program [PDF]

open access: yes, 2000
In spring 1999, the Anchorage Police Department and the Alaska Division of Juvenile Justice formed a partnership to enhance the supervision and services provided to juvenile probationers in Anchorage.
Giblin, Matthew
core  

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

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