Results 191 to 200 of about 11,283,501 (304)

Program Evaluation of Acupuncture and Massage Services Delivered for Symptom Management at a Community Cancer Clinic. [PDF]

JCO Oncol Pract
Booher AG, Rico C, Nouvini R, Killoran K, Drullinsky P, Maxwell S, Li S, Jutagir D, McConnell K, Godfrey H, Cadwell M, Casaw C, Rosa WE, Muñiz RC, Liou KT.   +14 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Evidence-Based Practice Policy Analysis and Program Evaluation Reporting Guidelines. [PDF]

J Nurs Care Qual
Waldrop JB, Dunlap JJ, Reynolds SS.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Enhancing Group Coaching Competencies in the National Diabetes Prevention Program: Evaluation of the Group Coaching Certificate Program. [PDF]

Am J Lifestyle Med
Smith K, Carmack S, Wolever RQ, Schultz C, Papalii MA, Williams AM, Thompson HL, Cline TR.   +7 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Effectiveness of the national vitamin D supplementation program: evaluation of children aged 0-3 years in Karabük province. [PDF]

J Health Popul Nutr
Deniz Y.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A Qualitative Program Evaluation Study on the Perceived Impact of Health and Nutrition Programs among Beneficiaries of a Civil Society Organization in the Philippines. [PDF]

Acta Med Philipp
Dela Luna KLG, Sy ADR, Rama-Sabandal RLCM, Jacinto CBK, Malimban RC, Sales BEG, Marollano RA, Marin AC.   +7 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source