Results 291 to 300 of about 24,429,365 (358)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Curriculum and program evaluation in medical education: a short systematic literature review. [PDF]

Ann Med Surg (Lond)
Ullah H, Huma S, Yasin G, Ashraf M, Tahir-Ud-Din Q, Shabana H, Sarfraz J.   +6 more
europepmc   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Establishing an Interprofessional Honor Society as an Extracurricular Health Professions Educational Bridge: A Formative Program Evaluation Case Study. [PDF]

AJPM Focus
Jadotte YT.
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Eating Disorders in Adolescents and Young Adults: A Program Evaluation of a Canadian Eating Disorder Treatment Program. [PDF]

Cureus
Dewar-Morgan C, Nippak P, Begum H, Remers S, Rosenberg-Yunger Z, Meyer JM, Nippak A.   +6 more
europepmc   +1 more source

The directors of resident support program: a program evaluation of a resident well-being and support innovation. [PDF]

BMC Med Educ
Ruzycki SM, des Ordons AR, Davis M, Steele JM, Tutu KO, Welikovitch L.   +5 more
europepmc   +1 more source

Acceptability and effectiveness of empathy-based provider training and community-level awareness activities on self-injectable contraceptive use in Niger, Lagos, and Oyo States, Nigeria: a mixed methods program evaluation. [PDF]

BMC Womens Health
Ontiri S, Rothschild CW, Tariq F, Adeleke O, Titus M, Raji M, Njogu J, Gibbs S, Swearingen R, Edet F.   +9 more
europepmc   +1 more source

Impact of a short-term pharmacy study abroad Program: student outcomes and program evaluation. [PDF]

BMC Res Notes
Elmokadem EM, Mahmoud AA, Bennett-Lenane H, Murphy KD, Khalil N.   +4 more
europepmc   +1 more source