Results 71 to 80 of about 4,694,538 (359)

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Tetroon evaluation program [PDF]

open access: yes
The actual volume of a constant volume superpressured tetrahedron shaped balloon changes as the amount of superpressure is changed. The experimental methods used to measure these changes in volume are described and results are presented.
Beemer, J. D., Markhardt, T. W.
core   +1 more source

Summary: More Than a Job Final Results from the Evaluation of the Center for Employment Opportunities Transitional Jobs Program [PDF]

open access: yes, 2012
The evaluation of the Center for Employment Opportunities (CEO) transitional jobs program is one of the most rigorous tests of an employment program for former prisoners in recent years.

core  

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Program Evaluation and Random Program Starts [PDF]

open access: yes
This paper discusses the evaluation problem using observational data when the timing of treatment is an outcome of a stochastic process. We show that, without additional assumptions, it is not possible to estimate the average treatment effect and ...
Per Johansson, Peter Fredriksson
core  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Project Exploration: 10-year Retrospective Program Evaluation [PDF]

open access: yes, 2010
Assesses the impact of a program giving low-income students of color hands-on science experience on science capacity, youth development, and engagement in communities of practice.
Bernadette Chi, Juna Z. Snow
core  

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

THE EVALUATION OF THE IMPLEMENTATION OF CONTRACTOR SAFETY MANAGEMENT SYSTEM (CSMS) PROGRAM ON TURNAROUND PROJECT (TA) AT PT. PUPUK SRIWIDJAJA (PUSRI) PALEMBANG

open access: yesJurnal Ilmu Kesehatan Masyarakat, 2016
Background :Turnaround is one of the done by contractor in which if it is not managed well, it could cause work accident. The purpose of this study was to evaluate the implementation of contractor safety management system (CSMS) program on turnaround ...
Muhammad Arif   +2 more
doaj   +1 more source

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