Results 71 to 80 of about 4,694,538 (359)
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Tetroon evaluation program [PDF]
The actual volume of a constant volume superpressured tetrahedron shaped balloon changes as the amount of superpressure is changed. The experimental methods used to measure these changes in volume are described and results are presented.
Beemer, J. D., Markhardt, T. W.
core +1 more source
Summary: More Than a Job Final Results from the Evaluation of the Center for Employment Opportunities Transitional Jobs Program [PDF]
The evaluation of the Center for Employment Opportunities (CEO) transitional jobs program is one of the most rigorous tests of an employment program for former prisoners in recent years.
core
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Program Evaluation and Random Program Starts [PDF]
This paper discusses the evaluation problem using observational data when the timing of treatment is an outcome of a stochastic process. We show that, without additional assumptions, it is not possible to estimate the average treatment effect and ...
Per Johansson, Peter Fredriksson
core
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Project Exploration: 10-year Retrospective Program Evaluation [PDF]
Assesses the impact of a program giving low-income students of color hands-on science experience on science capacity, youth development, and engagement in communities of practice.
Bernadette Chi, Juna Z. Snow
core
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Background :Turnaround is one of the done by contractor in which if it is not managed well, it could cause work accident. The purpose of this study was to evaluate the implementation of contractor safety management system (CSMS) program on turnaround ...
Muhammad Arif+2 more
doaj +1 more source