Results 51 to 60 of about 71,487 (291)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Static Slicing of Interprocedural Programs [PDF]

, 2012
Program slicing has many applications in a software development environment such as debugging, testing, anomaly detection, program understanding and many more.
Arya, Dheeraj Kumar, Kumar, Rakesh
core  

Using Program Slicing to Identify Faults in Software [PDF]

, 2006
This study explores the relationship between program slices and faults. The aim is to investigate whether the characteristics of program slices can be used to identify fault-prone software components.
Black, Sue, Counsell, Steve, Hall, Tracy, Wernick, Paul   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Diagnostics for stochastic genome-scale modeling via model slicing and debugging. [PDF]

PLoS ONE, 2014
Modeling of biological behavior has evolved from simple gene expression plots represented by mathematical equations to genome-scale systems biology networks. However, due to obstacles in complexity and scalability of creating genome-scale models, several
Kevin J Tsai, Chuan-Hsiung Chang
doaj   +1 more source

Development of a Tool for Slicing of Object-Oriented Program [PDF]

, 2014
Program slicing has many applications in a software development environment such as debugging, testing, anomaly detection, program understanding and many more.
Behera, Santosh Kumar
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Review on Program Slicing Techniques towards Program Comprehension Application

Journal of Computing Research and Innovation, 2018
Presently, the software system has grown in size. One of the main challenges faced by programmers is to keep up with thousand or million lines of source code that needs to be read and understood.
Rozita Kadar, Naemah Abdul Wahab, Jamal Othman   +2 more
doaj  

Graph neural network based approach to automatically assigning common weakness enumeration identifiers for vulnerabilities

Cybersecurity, 2023
Vulnerability reports are essential for improving software security since they record key information on vulnerabilities. In a report, CWE denotes the weakness of the vulnerability and thus helps quickly understand the cause of the vulnerability ...
Peng Liu, Wenzhe Ye, Haiying Duan, Xianxian Li, Shuyi Zhang, Chuanjian Yao, Yongnan Li   +6 more
doaj   +1 more source

Unions of slices are not slices [PDF]

Many approaches to slicing rely upon the 'fact' that the union of two static slices is a valid slice. It is known that static slices constructed using program dependence graph algorithms are valid slices (Reps and Yang, 1988).
De Lucia, A, Harman, M, Hierons, RM, Krinke, J   +3 more
core   +4 more sources