Results 51 to 60 of about 106 (62)

Therapeutic strategies to target RAS-mutant cancers

Nature Reviews Clinical Oncology, 2018
Ryan B Corcoran
exaly  

Target identification of natural medicine with chemical proteomics approach: probe synthesis, target fishing and protein identification

Signal Transduction and Targeted Therapy, 2020
Xiao Chen, Bo Zhu, Zhen Liang
exaly  

The drug–target residence time model: a 10-year retrospective

Nature Reviews Drug Discovery, 2015
Robert A Copeland
exaly  

Protein kinase C, an elusive therapeutic target?

Nature Reviews Drug Discovery, 2012
Daria Mochly-Rosen
exaly  

Drug–target residence time and its implications for lead optimization

Nature Reviews Drug Discovery, 2006
Robert A Copeland, Thomas D Meek
exaly  

β-Catenin hits chromatin: regulation of Wnt target gene activation

Nature Reviews Molecular Cell Biology, 2009
Christian Mosimann, George Hausmann, Konrad Basler   +2 more
exaly  

Lipid II as a target for antibiotics

Nature Reviews Drug Discovery, 2006
Eefjan Breukink
exaly  

Cellular bioenergetics as a target for obesity therapy

Nature Reviews Drug Discovery, 2010
Yu-Hua Tseng, C Ronald Kahn
exaly  

Target selection in drug discovery

Nature Reviews Drug Discovery, 2003
exaly  

Reliability of 'new drug target' claims called into question

Nature Reviews Drug Discovery, 2011
exaly