Results 21 to 30 of about 400,894 (299)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Local innovation system from a multi-stakeholder and participatory governance approach
The municipality of Consolación del Sur, like most of the Cuban municipalities, has the urgent need to solve the problems affecting its sustainable local development, based on the application of knowledge and innovation, from multi-stakeholder ...
Martha María Cruz Bravo +2 more
doaj
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Entre ficción y ciencia: El uso de la narrativa en la enseñanza de la ciencia
Usar narrativa para ayudar a la enseñanza de la ciencia, no es una idea nueva, pero en los últimos años han aparecido nuevos planes y programas de estudio en journals y en internet.
Andrea Chapela Saavedra
doaj +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
DESEMPENHO DOS PROGRAMAS DE PÓS-GRADUAÇÃO ACADÊMICOS EM CONTABILIDADE NO BRASIL NO TRIÊNIO 2010-2012 COM BASE NA PRODUÇÃO BIBLIOGRÁFICA VEICULADA EM PERIÓDICOS CIENTÍFICOS [PDF]
Este artigo tem como objetivo analisar o desempenho dos programas de pós-graduação em Contabilidade no Brasil no triênio 2010-2012 com base na produção bibliográfica veiculada em periódicos científicos.
MURCIA, FERNANDO DAL-RI +1 more
core
75 años de compromiso con la calidad: El modelo de servicio público televisivo de la BBC [PDF]
El 2 de noviembre de 2011 el servicio televisivo de la BBC cumplía 75 años. Durante este tiempo la BBC ha tenido que afrontar numerosos retos, que ha superado con éxito y que la han convertido en modelo de empresa pública de televisión.
Teresa Ojer
doaj
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Teaching and research experiences from third year undergraduate students in Nutrition
Background: Cuban higher education prioritizes the development of mother tongue among students. Sometimes cognitive deficiencies and lack of language skills can be perceived in expressing themselves.
Eugenio Jesús López Gómez +5 more
doaj
La combinación armoniosa de los objetivos de marketing comercial con la solución de problemas sociales condujo al surgimiento de un nuevo concepto: El marketing social enfocado al cambio de comportamiento de los ciudadanos.
Africa Calanchez Urribarri +3 more
doaj

