Results 121 to 130 of about 4,862,734 (358)

Challenges related to the implementation of the CCMDD programme in Sekhukhune clinics

open access: yesHealth SA Gesondheid: Journal of Interdisciplinary Health Sciences
Background: Implementation of the central chronic medicines dispensing and distribution (CCMDD) programme in most of Sekhukhune primary health care (PHC) has been challenging.
Ragosebo P. Sekopa   +1 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Australia Country Profile [PDF]

open access: yes, 2003
[From Introduction] This country study for Australia is part of the ILO project \u27Employment of People with Disabilities – the Impact of Legislation’ which aims to enhance the capacity of national governments in selected countries of Asia and East ...
InFocus Programme on Skills, Knowledge and Employability   +1 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Theoretical and methodological analysis of subject-subject interaction in a higher educational institution

open access: yesПроблеми сучасної психології, 2017
The research is devoted to the study of the subject-subject interaction at the higher educational institutions.The concept essence of subject-subject interaction has been clarified and its structure has been stipulated in the article.
N. Y. Hotsuliak, N. S. Slavina
doaj  

The theme field and arrangement of wall-painting in the area of Patriarchate of Peć and the influence on the wall-painting in East Herzegovina in the 16th and 17th century [PDF]

open access: yesBaština, 2018
The Serbian wall painting in the churches of bigger dimensions in the area of Patriarchate of Peć in the 16th and 17th century was very abundant and various, primarily relying on the iconographic solutions from the 13th and 14th century, while in the ...
Lojović-Milinić Nina M.
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Klein's programme and Quantum Mechanics

open access: yes, 2015
We review the geometrical formulation of Quantum Mechanics to identify, according to Klein's programme, the corresponding group of transformations. For closed systems, it is the unitary group.
Clemente-Gallardo, J., Marmo, G.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Evaluation of the whanau carers training programme delivered by LIFE Unlimited [PDF]

open access: yes, 2004
In response to the needs of Maori informal carers, a training programme was developed for whanau carers in the Waikato region. It was delivered by LIFE Unlimited.
Ashwell, Allanah   +2 more
core   +1 more source

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