Results 131 to 140 of about 4,862,734 (358)
The spandrels of San Marco and the Panglossian paradigm: a critique of the adaptationist programme
Proceedings of the Royal Society of London. Series B. Biological Sciences, 1979 S. Gould, R. Lewontin
semanticscholar +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Références bibliographiques du dossier « programmes et politiques éducatives »
Revue Internationale d’Éducation de Sèvres, 1996 Maryannick Vervisch-Lestrade
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Laos legislative drafting programme [PDF]
, 1994 Draft documents, proposals, notes, and other various papers related to the Seidman's efforts to develop a legislative drafting programme in Lao People's Democratic Republic (PDR) between 1994 and 1997. This project was developed with support from the Lao
Seidman, Ann, Seidman, Robert B.
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Climate Change Adaptation and Mitigation: Implications for land acquisition and population relocation [PDF]
In response to the challenge of climate change, governments of developing countries are evolving adaptation and mitigation programmes for which they are seeking international financing.
Foresight Programme, UK Government +1 more
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Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Political, economic and social characteristics of political parties' programmes in Serbia until 1918 [PDF]
Sociološki Pregled, 2019 In this paper, we merely begin to discuss the establishment of political ideas, beginnings of political thought and political streams at the end of the first half of the 19th century, as the basis upon which political parties were formed several decades ...
Kočović Dragoslav R.
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
, 2014 This paper explores how system-wide approaches to obesity prevention were 'theorised' and translated into practice in the 'Healthy Towns' programme implemented in nine areas in England.
Cummins, Steven +6 more
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