Results 61 to 70 of about 433 (250)

An Interactive, Heuristic Program for Learning Transformational Grammars [PDF]

open access: yes, 1970
An interactive system for learning transformational grammars of natural languages has been programmed in ALGOL and is operational on a B5500 timesharing system.
Klein, Sheldon, Kuppin, Michael A.
core  

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

open access: yesAdvanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li   +14 more
wiley   +1 more source

Context-free grammars with graph control [PDF]

open access: yes
Context-free grammars with graph control provide a general framework for the various types of context-free grammars with regulated rewriting. The vertices or edges of the directed graph are labeled with the productions of the grammar. The only strings in
Cook, Curtis R.
core   +1 more source

Visuelle, interaktive 3D Spatial Grammars in CAD für die rechnerbasierte Designsynthese [PDF]

open access: yes, 2013
Spatial grammars provide a method for rule-based generation of geometry wich have yet to find general application within mechanical engineering CAD systems. Existing grammars are mostly programmed as stand alone systems for one specific application. This
Hoisl, Frank
core  

CREAT: A CRISPR‐Based Genome Trimming Strategy for Systematic Identification of Dispensable Regions and Rapid Genome Reduction

open access: yesAdvanced Science, EarlyView.
Current genome‐reduction methods work in a trial‐and‐error fashion, constituting a long‐standing bottleneck in the research. We developed CREAT (CRISPR‐based genome trimming with a multi‐homology‐arm template), a CRISPR‐based genetic approach that enables systematically classifying essential versus non‐essential genomic regions and subsequently ...
Guanhua Yuan   +7 more
wiley   +1 more source

A survey on syntactic pattern recognition methods in bioinformatics [PDF]

open access: yes
Formal tools and models of syntactic pattern recognition which are used inbioinformatics are introduced and characterized in the paper. They include,among others: stochastic (string) grammars and automata, hidden Markovmodels, programmed grammars ...
Flasiński, Mariusz
core   +2 more sources

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

open access: yesAdvanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun   +14 more
wiley   +1 more source

Goals as Emergent Autopoietic Processes. [PDF]

open access: yesFront Bioeng Biotechnol, 2021
Veloz T.
europepmc   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

open access: yesAdvanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio   +6 more
wiley   +1 more source

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