Results 111 to 120 of about 9,061,188 (344)
Domain-Independent Dynamic Programming
Manuscript submitted to Artificial ...
Kuroiwa, Ryo, Beck, J. Christopher
openaire +2 more sources
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Recurrence Domains: Their Unification and Application to Logic Programming
Information and Computation, 1995 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Chen, H., Hsiang, Jieh
openaire +2 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
FURY: Fuzzy unification and resolution based on edit distance [PDF]
, 2000 We present a theoretically founded framework for fuzzy unification and resolution based on edit distance over trees. Our framework extends classical unification and resolution conservatively. We prove important properties of the framework and develop
Gilbert, D, Schroeder, M
core +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Cross-domain recommendation in MOOCs: A graph capsule network approach with transfer learning
Computers and Education: Artificial IntelligenceCross-domain recommendation systems enhance target domain performance through multi-domain knowledge integration. With the rapid development of artificial intelligence, the growing demand for programming skills has intensified the need for joint ...
Lian Yuanfeng, Zhuang Yongqi
doaj
A Domain-Independent Window Approach to Multiclass Object Detection Using Genetic Programming
EURASIP Journal on Advances in Signal Processing, 2003 This paper describes a domain-independent approach to the use of genetic programming for object detection problems in which the locations of small objects of multiple classes in large images must be found.
Ciesielski Victor B +2 more
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Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Computers in Human Behavior ReportsAnxiety and enjoyment are important influences of success. However, there are few studies investigating how anxiety and enjoyment change when university students first engage with an unfamiliar subject and how they affect each other.
Anke Maria Weber +5 more
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