Results 71 to 80 of about 9,061,188 (344)
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Domain-Specific Automatic Programming
IEEE Transactions on Software Engineering, 1985 Domain knowledge is crucial to an automatic programming system and the interaction between domain knowledge and programming at the current time. The NIX project at Schlumberger-Doll Research has been investigating this issue in the context of two application domains related to oil well logging.
openaire +2 more sources
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Sustaining interaction in a mathematical community of practice [PDF]
, 2005 This paper focuses on an activity in which students explore sequences through a game, using ToonTalk programming and a web-based collaboration system. Our analytical framework combines theory of communities of practice with domain epistemology.
De Lacerda Matos, João Filipe +3 more
core +3 more sources
Scenic: A Language for Scenario Specification and Scene Generation
, 2019 We propose a new probabilistic programming language for the design and analysis of perception systems, especially those based on machine learning. Specifically, we consider the problems of training a perception system to handle rare events, testing its ...
Dosovitskiy Alexey +15 more
core +1 more source
Domain Adaptation for Automated Program Repair
, 2022 Automated Program Repair (APR) is defined as the process of fixing a bug/defect in the source code by an automated tool. APR methods have recently experienced promising results by leveraging state-of-the-art Neural Language Processing (NLP) techniques.
openaire +1 more source
Complete logic programs with domain-closure axiom
The Journal of Logic Programming, 1988 Summary: Complete logic programs augmented with the domain-closure axiom are proposed as the reference theory for logic programming with negation as failure. An inference rule corresponding to ``proof by case analysis'' is proved correct within this framework.
MANCARELLA, PAOLO MARIA +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
myDIG: Personalized Illicit Domain-Specific Knowledge Discovery with No Programming
Future Internet, 2019 With advances in machine learning, knowledge discovery systems have become very complicated to set up, requiring extensive tuning and programming effort.
Mayank Kejriwal, Pedro Szekely
doaj +1 more source
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source