Results 91 to 100 of about 9,721,114 (299)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
On reliability, safety, and readability of programming languages on the example of Ada language
Informatika, 2019 A few small suggestions of language design reflect the author's views are presented. These suggestions are mainly related to the reliability and safety of simple, typical structures and statements in programming: typification, compile-time elaborations ...
A. V. Leont’ev
doaj
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Research on network programmable technologies
Dianxin kexue, 2016 Network programmable technologies enforce the capacity of flexible configuration and resource composition by providing network devices with programmable interfaces.
Lijun XIE +5 more
doaj
THE INFLUENCE OF A TIMED BROWSER (*TB) INTO WEB-BASED INSTRUCTION ON COMPUTER SCIENCE STUDENTS’ MOTIVATION TO LEARN PROGRAMMING LANGUAGES: PRELIMINARY FINDINGS [PDF]
Studia Universitatis Babeş-Bolyai. Psychologia-Paedagogia, 2014 . This article presents the preliminary findings of research which aimed to explore the influence of a Timed Browser (*TB) as an innovative pedagogy on computer science students’ motivation to learn programming language.
UDI LAVI, VASILE CHIŞ
doaj
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Distance education with Moodle in engineering education: online programming assignments compilation
Tehnički Glasnik, 2018 The concept of distance education systems is a concept that applies to all levels of education, including universities. The use of distance education systems has increased considerably in universities today.
Mümine Kaya Keleş +1 more
doaj +1 more source