Results 51 to 60 of about 1,044,682 (335)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

CONTEMPORARY DATA SCIENCE FOR FINANCE STUDENTS. ESSENTIAL FEATURES OF COMMONLY USED STATISTICAL SOFTWARE - A COMPARATIVE STUDY [PDF]

open access: yesBusiness Excellence and Management, 2019
This paper inventories some of the essential traits of the software preferred by researchers, students and professors, such as R or RStudio, or Matlab and also their possible utilizations.
Mădălina Viorica ION (MANU)   +1 more
doaj  

A NEW PROGRAMMING LANGUAGE: GO PROGRAMMING LANGUAGE

open access: yes, 2018
Everyone knows that hardware does not mean anything without software. Software is developed by programming languages. One of the most important factors determining the reach of software is the characteristics of the programming language. Many rich applications can be developed with a language that is fast, easy to learn, and has a large library.
OF, MUSTAFA, ÇAKIR, BURAK
openaire   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Conceptualising Programming Language Semantics

open access: yesPhilosophies
The semantics of programming languages tend to be discussed with high levels of formality; much of the previous research—both philosophical and historical—has investigated them from this perspective.
Troy Kaighin Astarte
doaj   +1 more source

An Assessment of the Teaching-Learning Methodologies Used in the Introductory Programming Courses at a Brazilian University

open access: yesInformatics in Education, 2018
The teaching-learning methodology adopted in the Introduction to Computer Science classes may be a process that makes it difficult to understand the principles of programming language for undergraduate students in Computer Science and related areas ...
Edna Dias CANEDO   +2 more
doaj   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

A language of specified programs

open access: yesScience of Computer Programming, 1985
We describe a language of specified programs devised to form a basis for a system for the development of provably-correct programs. A specified program, as introduced by Blikle and then developed in this paper, consists of statements and declarations (in our language these are standard sequential, conditional and loop statements, blocks with local ...
openaire   +3 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

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