Results 101 to 110 of about 948,913 (337)

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Report on Progress of Ophthalmology [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1881
n ...
openaire   +3 more sources

Report on Progress of Dentistry [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1881
n ...
openaire   +2 more sources

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

A progress report… dates of planting for asparagus production

open access: yesCalifornia Agriculture, 1971
These tests show that a good initial stand of asparagus can be obtained through direct seeding from early spring to late summer; however, the final established stand was dependent upon the cultural practice following the first season of growth. Plantings
F Takatori, J Stillman, F Souther
doaj  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

A progress report: Redesigning pear trees for mechanical harvesting

open access: yesCalifornia Agriculture, 1964
Mechanical harvesting of Bartlett pears was attempted in 1960 using a block of sixty-year-old trees, designed specifically for hand harvesting, at the George and Walter Brown pear ranch, Santa Clara County. The lower limbs were so near to the ground that
L McNelly, L Barnard
doaj  

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