Results 101 to 110 of about 10,571,700 (283)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A progress report: Redesigning pear trees for mechanical harvesting
Mechanical harvesting of Bartlett pears was attempted in 1960 using a block of sixty-year-old trees, designed specifically for hand harvesting, at the George and Walter Brown pear ranch, Santa Clara County. The lower limbs were so near to the ground that
L McNelly, L Barnard
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
A progress report… dates of planting for asparagus production
These tests show that a good initial stand of asparagus can be obtained through direct seeding from early spring to late summer; however, the final established stand was dependent upon the cultural practice following the first season of growth. Plantings
F Takatori, J Stillman, F Souther
doaj
A Development of an IoT-Based Connected University System: Progress Report. [PDF]
Matuska S, Machaj J, Hutar M, Brida P.
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A progress report: Paraquat for range seeding without cultivation
Millions of acres of California rangelands that could otherwise be improved by re-seeding are located on terrain that is steep, erodable, or too rocky for cultivation. Recent research has shown that these ranges can be successfully seeded by spraying the
B Kay
doaj
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
A progress report… bee pollination in cucumbers for pickling
Selective admission of bees to cucumber blossoms (through use of a field screening procedure) resulted in production of fruit yields roughly proportional to the length of time the bees were admitted and to the field activity level of bees during that ...
W Seyman +4 more
doaj

