Results 151 to 160 of about 954,648 (283)

Introduction to Quarterly Progress Report

, 1949
Contains cover page and an introduction.This report, the fourteenth in a series of quarterly progress reports issued by the Research Laboratory of Electronics, contains a review of the research activities of the Laboratory during the three-month period ...
Hill, Albert G., Wiesner, Jerome B.
core  

Neuro-Oncology Biotech Industry Progress Report 2025. [PDF]

Cureus
Croft ZA, Thomas G, Keister E, McDermott M, Syed S, Latzman S, Wong T, Serulle Y, Langer DJ, D'Amico R, Boockvar J.   +10 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Exploiting biomaterial approaches to manufacture an artificial trabecular meshwork: A progress report. [PDF]

Biomater Biosyst, 2021
Crouch DJ, Sheridan CM, D'Sa RA, Willoughby CE, Bosworth LA.   +4 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

NPRP 6-885-2-364 - Progress Report Number 5- "Localization of EEG Abnormalities for Improving Brain Monitoring of Newborn Babies at Risk of Brain Injury using a multichannel time-frequency signal processing approach"

, 2016
This is a progress report for the project NPRP 6 - 885 - 2 – 364 - Progress Report Number 5- Localization of EEG Abnormalities for Improving Brain Monitoring of Newborn Babies at Risk of Brain Injury using a multichannel time-frequency signal processing ...
Boashash, B., Colditz, Paul
core  

Response Assessment in Neuro-Oncology (RANO) 2009-2025: Broad scope and implementation-A progress report. [PDF]

Neuro Oncol
van den Bent MJ, Vogelbaum MA, Cloughesy T, Galldiks N, Albert NL, Tonn JC, Avila E, Fangusaro J, Mirsky D, Sahgal A, Soffietti R, Karschnia P, Mehta M, Kim MM, Boele F, Huse JT, Nayak L, Lim-Fat MJ, le Rhun E, Desjardins A, Lee EQ, Chukwueke U, Koekkoek JAF, Mendoza T, Loughan AR, Budhu JA, Bakas S, Huang RY, Villanueva-Meyer JE, Leone JP, Okada H, Reardon DA, Bi WL, Wen PY, Chang SM.   +34 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

IJD ® 2012: A Progress Report

Indian Journal of Dermatology, 2013
Koushik Lahiri
doaj   +1 more source