Results 261 to 270 of about 16,801,423 (422)

Study of St. Clair fly ash in non-air-entrained concrete made with Portland and Portland-slag cements : progress report [PDF]

, 1957
F. E. Legg, Ralph H. Vogler
openalex  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Development of procedures for the identification of minor phases of heat-resistant alloys by electron diffraction and electron microscopy : progress report no. 10 : for period 15 October 1954 to 15 January 1955 [PDF]

, 1955
L. O. Brockway, W. C. Bigelow, J. A. Amy
openalex  

The roles and applications of extracellular vesicles in cancer

Molecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Cleveland Clinic Continuous-Flow Total Artificial Heart: Progress Report and Technology Update. [PDF]

ASAIO J
Kuroda T, Miyagi C, Polakowski AR, Flick CR, Kuban BD, Fukamachi K, Karimov JH.   +6 more
europepmc   +1 more source

Work in progress report of a multicentre retrospective observational study to evaluate the association between the airflows and the intrapleural pressures digitally recorded after video-assisted lobectomy. [PDF]

Interact Cardiovasc Thorac Surg, 2021
Bertolaccini L, Viti A, Bertoglio P, Imperatori A, Morelli A, Zaraca F, Spaggiari L, Crisci R, In-Pression Trial Study Group.   +8 more
europepmc   +1 more source

Construction of a sector shock tube : progress report no. 7 [PDF]

, 1957
Otto Laporte, A. L. Cole
openalex  

Quarterly progress report January, February, March, 1959

, 1959

openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Curriculum 2000: implementation progress report [PDF]

, 2000

core