Results 71 to 80 of about 10,571,700 (283)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Introduction to Quarterly Progress Report

open access: yes, 1972
Contains title page, list of grants and sponsors and an introduction.This report, the hundred and sixth in a series of quarterly progress reports issued by the Research Laboratory of Electronics, contains a review of the research activities of the ...
Zimmermann, Henry J.   +2 more
core   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Introduction to Quarterly Progress Report

open access: yes, 1973
Contains title page, list of grants and sponsors and an introduction.This report, the hundred and tenth in a series of quarterly progress reports issued by the Research Laboratory of Electronics, contains a review of the research activities of the ...
Zimmermann, Henry J.   +2 more
core   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Nonsexist Language: A Progress Report

open access: yesCanadian Journal of Education, 1993
What do students entering university know about inclusive language? This question led me to design a survey and distribute it to 348 students at a university in Eastern Canada.
Deborah Kennedy
doaj   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Recon Pilot Project: A Progress Report

open access: yesInformation Technology and Libraries, 1970
A synthesis of the progress report submitted by the Library of Congress to the Council on Library Resources under an Officers Grant to initiate the RECON Pilot Project that gives an overview of the project and the progress made from August-November 1969 ...
Henriette D. Avram
doaj   +1 more source

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