Results 91 to 100 of about 9,033,749 (289)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Radiative Return: a progress on FSR tests
To improve the accuracy of the e+e- -> pi+pi-gamma Radiative Return method, one has to control the theoretical uncertainty of the final-state photon emission. It is of particular importance at DAPHNE for the analysis, where cuts are relaxed to cover the threshold region.
Ivashyn, Sergiy +2 more
openaire +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Family Sculpture with Playmobil Pieces
Mit dem FSPlay werden innere "Arbeitsmodelle" (Schemata) von Bindungs-/Familien-/Partnerschafts-/Freundschaftsbeziehungen erhoben. Anhand mehrerer Spielfiguren sollen eine oder mehrere Skulpturen gestaltet werden, z. B.
Sydow, K. v.
core +1 more source
Progress test has been created with the necessity of an assessment method align with problem-based learning. Although it was specifically created to overcome the limitations of traditional assessment for problem-based learning, nowadays is used by ...
Dario Cecilio-Fernandes +2 more
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
ECR-G-10. Experiences in Close Relationships Scale - German 10-Item Short Form
Der ECR-G-10, die Kurzform des Bochumer Bindungsfragebogens (BoBi), erfasst mit 10 Items das Erleben und Verhalten in der partnerschaftlichen Bindung im Erwachsenenalter und wurde auf der Grundlage des zweidimensionalen Modells von Bindung, das zwischen ...
Rohmann, E., Sattel, H., Neumann, E.
core +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source

