Results 241 to 250 of about 320,938 (307)

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source

The Effect of Systemic Steroid Use on the Success of Core Decompression in Non-Traumatic Early-Stage Femoral Head Osteonecrosis. [PDF]

Sisli Etfal Hastan Tip Bul
Pehlivanoglu G, Cimen O, Koksal A.
europepmc   +1 more source

Lithiophilic Current Collector Without Interfacial Penalty in Zero‐Excess Lithium Metal Batteries

Advanced Science, EarlyView.
Bilayer lithiophilic coatings are introduced to overcome the structural fragility of conventional single‐layer current collectors in zero‐excess Li‐metal batteries (ZE‐LMBs). By integrating density functional theory with electrochemical analyses, the Ag‐outer/Pt‐inner configuration enables uniform Li deposition, robust SEI formation, and persistent ...
Jiyeon Seo, Sangseob Lee, Seojin Jeon, Minhong Lim, Hyegang Koo, Seung‐Tae Hong, Woosun Jang, Aloysius Soon, Hongkyung Lee   +8 more
wiley   +1 more source

Marginal Band Collapsing: Structural Insights Into Shear-Induced Platelet Activation Relevant to Circulatory Assist Devices. [PDF]

ASAIO J
Perez R, Ho K, Vandenberge J, Kim N, Tran D, Han D, Sun W, Wang S, Griffith BP, Wu ZJ.   +9 more
europepmc   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Successful management of Pott's disease in a young woman with 32 weeks of pregnancy: a rare case report. [PDF]

Radiol Case Rep
Maliha AR, Billah MM, Arafin MM, Khalil I, Tabassum T.   +4 more
europepmc   +1 more source

Case of a 35-Year-Old Man With Pain With Sneezing and Leg Weakness Causing Collapse. [PDF]

Ann Clin Transl Neurol
Hsu J, Schoedel K, Plotzker A, Doherty L.   +3 more
europepmc   +1 more source

Biomimetic Spiral-Reinforced Honeycomb for Integrated Energy Absorption Under Complex Loading Scenarios. [PDF]

Biomimetics (Basel)
Nian J, Huang Z, Zhao Y, Liu K.
europepmc   +1 more source

A Rare Case of Mediastinal NUT (Nuclear Protein in Testis) Carcinoma Presenting with Acute Respiratory Failure: A Case Report. [PDF]

Int Med Case Rep J
Javed H, Ahmad A, Rehman A, Mikula MW.
europepmc   +1 more source

Subchondral Insufficiency Fracture of the Femoral Head in a Terminal Cancer Patient Treated by Total Hip Arthroplasty. [PDF]

J Orthop Case Rep
Yuasa A, Kobayashi H, Horiuchi K.
europepmc   +1 more source