Results 41 to 50 of about 63,976 (299)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Overall buckling of lightweight stiffened panels using an adapted orthotropic plate method
, 2015 The ultimate longitudinal bending strength of thin plated steel structures such as box girder bridges and ship hulls can be determined using an incremental–iterative procedure known as the Smith progressive collapse method.
Downes, J., Dow, R.S., Benson, S.
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Progressive collapse of structures: A discussion on annotated nomenclature [PDF]
, 2021 The study of progressive collapse and structural robustness has advanced significantly after 9/11 event. There is a growing interest in the phenomenon, as well as in the development of numerical and experimental techniques that have led to great progress
Sheidaii, M R +3 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Robustness of steel framed buildings [PDF]
, 2006 Since the catastrophic failures of the twin towers at the World Trade Centre, avoidance of progressive collapse has become a major concern of designers of multi-storey buildings.
Liu, Ru
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Optimisation of Cable Dome Structure Design for Progressive Collapse Resistance
Applied Sciences, 2023 Since the literature lacks an effective analysis method of collapse mechanisms and optimisation design theory for progressive collapse resistance of cable dome structure, a structural performance-based optimisation approach was proposed to improve the ...
Lian-Meng Chen +6 more
doaj +1 more source
A simplified simulation method for progressive collapse of reinforced concrete slabs
, 2016 Floor slabs are important components of frame structures which largely affect the structural progressive collapse performance. This paper presents a simplified numerical simulation method for reinforced concrete (RC) slabs. A RC slab is discretized along
Lu, Xin-Zheng +3 more
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