Results 271 to 280 of about 82,833 (333)

Outcome of Progressive Multifocal Leukoencephalopathy Treated by Interleukin‐7

Annals of Neurology, 2022
Restoring anti‐JC virus (JCV) immunity is the only treatment of progressive multifocal leukoencephalopathy (PML). Interleukin‐7 is a cytokine that increases number and function of T cells. We analyzed a population of PML patients who received recombinant
Rébecca Lajaunie, Ilaria Mainardi, J. Gasnault, V. Rousseau, A. Tarantino, A. Sommet, P. Cinque, G. Martin-Blondel   +7 more
semanticscholar   +1 more source

Progressive multifocal leukoencephalopathy in dimethyl fumarate-treated multiple sclerosis patients

Multiple Sclerosis, 2020
Dimethyl fumarate (DMF), a fumaric acid with antioxidant and immunomodulatory properties, is among the most commonly used oral therapies for relapsing multiple sclerosis (MS).
Allison Jordan, Jennifer Yang, Caitlyn J Fisher, M. Racke, Y. Mao-Draayer   +4 more
semanticscholar   +1 more source

Progressive Multifocal Leukoencephalopathy

European Neurology, 1971
The present paper reports on a case of progressive multifocal leukoencephalopathy, with certain particularities.
C. Arseni, Fl. Nereanţiu
openaire   +5 more sources

Progressive Multifocal Leukoencephalopathy

Neurologic Clinics, 1984
PML is a progressive opportunistic infection of the CNS caused by a commonly occurring virus that may become manifest in the context of reduced host resistance in persons of any age. The authors review the disease and its causes, including a discussion of treatment attempts and differential diagnoses.
Benjamin Rix Brooks, Duard L. Walker
openaire   +2 more sources

Progressive Multifocal Leukoencephalopathy

Seminars in Neurology, 1999
Before the AIDS epidemic, progressive multifocal leukoencephalopathy (PML) was a rare disorder occurring most often in association with leukemia and lymphoma. Current estimates indicate that PML ultimately develops in up to 5% of all patients with AIDS.
Eugene O. Major, Joseph R. Berger
openaire   +3 more sources

Progressive Multifocal Leukoencephalopathy

Archives of Internal Medicine, 1963
Progressive multifocal leukoencephalopathy (PML) is a subacute demyelinating disease apparently resulting from the selective destruction of oligodendrocytes by papovaviruses. The pathology and pathogenesis of PML are distinct from those of the other slow infections of the human nervous system.
John T. Headington, Robert F. Johnston, Robert A. Green   +2 more
openaire   +3 more sources

Treatment of Progressive Multifocal Leukoencephalopathy with Nivolumab.

New England Journal of Medicine, 2019
Treatment of PML with Nivolumab A patient with severe idiopathic lymphopenia and progressive multifocal leukoencephalopathy had T-cell exhaustion and high expression of immune checkpoint markers.
O. Walter, E. Treiner, F. Bonneville, C. Mengelle, F. Vergez, F. Lerebours, P. Delobel, R. Liblau, G. Martin-Blondel   +8 more
semanticscholar   +1 more source

Progressive multifocal leukoencephalopathy

Current Infectious Disease Reports, 2001
Progressive multifocal leukoencephalopathy is a subacute demyelinating disease that occurs in patients with defects in cell-mediated immunity, including those with AIDS and lymphoproliferative disorders. It is caused by reactivation of JC virus (JCV), which infects 70% to 90% of the population by adulthood, but remains latent in normal hosts.
Anna R. Thorner, Joel T. Katz
openaire   +3 more sources

Progressive Multifocal Leukoencephalopathy

Journal of Neuroimmunology, 2011
Progressive multifocal leukoencephalopathy (PML) is a disease of the central nervous system (CNS) with destructive infection of oligodendrocytes by JC virus. PML belongs to the opportunistic infections. It is observed in patients with HIV infection, lymphoid malignancies, after organ- and stem cell transplantations and more recently in the context of ...
openaire   +3 more sources