The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
PROGRESSIVE SPINAL MUSCULAR ATROPHY OF INFANTS (WERDNIG-HOFFMANN TYPE) [PDF]
, 1912 F. E. Batten, Gordon Holmes
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Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice
Advanced Science, EarlyView.Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu +14 more
wiley +1 more source
Advanced Science, EarlyView.An integral healable dielectric elastomer actuator (ISDEA) with a premature breakdown warning function is prepared based on the combination of electroluminescent dielectric elastomer and transparent compliant electrodes. Several ISDEAs are combined to construct soft anti‐counterfeiting labels and soft intelligent keyboards, expanding their potential ...
Yanze Liu +5 more
wiley +1 more source
A case of bulbospinal muscular atrophy with large fasciculation manifesting as spinal myoclonus
Clinical Neurophysiology Practice, 2017 Objective: This paper reports a patient with bulbospinal muscular atrophy (BSMA) who presented with spinal myoclonus, documented by video and surface electromyography.
Manabu Inoue +6 more
doaj
REPORT OF A CASE OF PROGRESSIVE MUSCULAR ATROPHY WITH BULBAR SYMPTOMS; THE ATROPHY LIMITED TO THE LEFT UPPER EXTREMITY, THE ABDUCTOR INDICIS OF THE RIGHT HAND, AND THE TONGUE, WHICH IS AFFECTED BILATERALLY, PREDOMINANTLY ON THE LEFT SIDE [PDF]
, 1887 W R BRIDSALL
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Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response
Advanced Science, EarlyView.This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li +15 more
wiley +1 more source
The Life-Saving Impact of Early Diagnosis and Treatment for Spinal Muscular Atrophy Type 1
Pakistan Journal of Medicine and DentistrySpinal muscular atrophy (SMA) is a hereditary neuromuscular condition caused by mutations in the Survival Motor Neuron 1 gene. This report presents a clinical description of a case diagnosed with SMA and highlights the significance of early recognition ...
Almas Siddique +2 more
doaj +1 more source
Necessity of physical rehabilitation in a patient with Duchenne progressive muscular dystrophy
Medisan, 2021 The case report of an 18 years adolescent is presented. He was assisted at Armando García Aspurú Teaching Polyclinic in Santiago de Cuba due to a history of psychomotor development retardation, wandering march, frequent falls, positive Gowers sign ...
Adriana Elisa Morales Tejeda +2 more
doaj
A CASE OF PROGRESSIVE MUSCULAR ATROPHY OF THE PERONEAL TYPE. [PDF]
The Journal of Nervous and Mental Disease, 1907 n ...
openaire +3 more sources