Results 261 to 270 of about 121,688 (385)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Surgical Access for Intrathecal Therapy in Spinal Muscular Atrophy with Spinal Fusion: Long-Term Outcomes of Lumbar Laminectomy. [PDF]

J Clin Med
Potaczek T, Duda S, Adamczyk J.
europepmc   +1 more source

TBCE Mutations Cause Early-Onset Progressive Encephalopathy with Distal Spinal Muscular Atrophy.

American Journal of Human Genetics, 2016
A. Sferra, G. Baillat, T. Rizza, S. Barresi, E. Flex, G. Tasca, A. D’Amico, E. Bellacchio, A. Ciolfi, V. Caputo, S. Cecchetti, A. Torella, G. Zanni, D. Diodato, E. Piermarini, M. Niceta, A. Coppola, E. Tedeschi, D. Martinelli, C. Dionisi-Vici, V. Nigro, B. Dallapiccola, C. Compagnucci, M. Tartaglia, G. Haase, E. Bertini   +25 more
semanticscholar   +1 more source

Food Toxicology and Safety: Evaluating Dietary Risks and Functional Ingredients

Food Bioengineering, EarlyView.
The pyramid's foundation reminds us that true health begins with daily habits—engage in 30–60 min of physical activity, nurture social connections and secure 7–9 h of restorative sleep each night to support metabolism, mood regulation, and hormonal balance—while continuously hydrating with 8–12 glasses of water and unsweetened herbal infusions (green ...
Sujaritha Jayaraj, Lavanya Kothandan, Vijay Babu Murugan, Saravana Kumar Prakash, Vandhana Vijayakumar, Elizabeth Rani   +5 more
wiley   +1 more source

Quantitative cervical cord MRI in spinal muscular atrophy: a sensitive imaging biomarker of disease evolution and treatment. [PDF]

J Neurol
Asteggiano C, Mazzocchi L, Farina L, Paoletti M, Barzaghi L, Caverzasi E, Parravicini S, Dainesi MI, Gardani A, Savini G, Bergsland N, Ballante E, Wheeler-Kingshott CAMG, Berardinelli A, Pichiecchio A.   +14 more
europepmc   +1 more source

Insights into the interconnection of sarcopenia in heart failure

ESC Heart Failure, EarlyView.
Zhengyang Ge, Yanming Wu, Biao Wang
wiley   +1 more source

In Vitro Antihyperglycemic, Antioxidant, and Technofunctional Properties of Fonio Millet Instant Breakfast Meal Enriched With Food By‐Products

Future Postharvest and Food, EarlyView.
ABSTRACT Valorizing agro by‐products and using underutilized food crops are two important ways to guarantee sustained food and health security in the tropics. Hence, this study was to create a functional breakfast meal using a combination of soy cake (SC), cocoa bean shell (CBS), and germinated fonio millet.
Olusola Samuel Jolayemi, Durosimi Yisa, Shukurat Abolore Ismaila, Oluwapelumi Esther Foluso, Modesola Dorcas Boboye   +4 more
wiley   +1 more source

Kennedy Disease in Latin America: Two New Mexican Cases and a Systematic Review of Regional Reports. [PDF]

Cureus
Martínez-Zamora CA, Vidal-Michaca SU, Rubio C, Ramírez-García MÁ.   +3 more
europepmc   +1 more source

Non-progressive juvenile spinal muscular atrophy of the distal upper limb (Hirayama's disease): a clinical variant of the benign monomelic amyotrophy [PDF]

, 2000
Osvaldo J. M. Nascimento, Marcos R. G. de Freitas   +1 more
openalex   +1 more source