Results 31 to 40 of about 8,171 (145)

Young-onset Alzheimer’s dementia mimicking progressive myoclonic epilepsy spectrum

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2023
Background Young-onset Alzheimer’s dementia (YOAD) refers to the onset of disease before the age of 40 years. Classical AD typically presents with memory impairment with involvement of other cognitive domains like language, visuospatial orientation.
Rohan Mahale, Gautam Arunachal, Debayan Dutta, N. Venkatachalam, Hansashree Padmanabha   +4 more
doaj   +1 more source

Lafora Disease: A Case Report of Progressive Myoclonic Epilepsy

Case Reports in Clinical Practice, 2023
Lafora disease is a rare genetic disease caused by the accumulation of malformed glycogen products in the tissues. The disease usually manifests with idiopathic generalized tonic colonic seizures with poor response to antiepileptic drugs (AEDs).
Sahar Delavari, Sogol Olamazadeh, Nima Ameli, Bahareh Pourghaz, Abbas Tafakhori   +4 more
doaj   +1 more source

Seizure remission and improvement of neurological function in sialidosis with perampanel therapy

Epilepsy and Behavior Case Reports, 2018
A 15-year-old boy experienced myoclonic seizures for 3 years. He initially had occasional myoclonus, gradually progressive ataxia, tremors, and psychomotor and speech regression developed. Eventually, he exhibited nearly continuous myoclonus. He received
Su-Ching Hu, Kun-Long Hung, Hui-Ju Chen, Wang-Tso Lee   +3 more
doaj   +1 more source

Clinical phenotype features and genetic etiologies of 38 children with progressive myoclonic epilepsy

Acta Epileptologica, 2020
Background Progressive myoclonic epilepsy (PME) is a group of neurodegenerative diseases with genetic heterogeneity and phenotypic similarities, and many cases remain unknown of the genetic causes. This study is aim to summarize the clinical features and
Jing Zhang, Ying Yang, Xueyang Niu, Jiaoyang Chen, Wei Sun, Changhong Ding, Lifang Dai, Liping Zhang, Qi Zeng, Yi Chen, Xiaojuan Tian, Xiaoling Yang, Taoyun Ji, Zhixian Yang, Yanling Yang, Yuwu Jiang, Yuehua Zhang   +16 more
doaj   +1 more source

Periodic electroencephalogram discharges in a case of Lafora body disease: An unusual finding

Annals of Indian Academy of Neurology, 2016
Lafora body disease (LBD) is a form of progressive myoclonic epilepsy, characterized by seizures, myoclonic jerks, cognitive decline, ataxia, and intracellular polyglucosan inclusion bodies (Lafora bodies) in the neurons, heart, skeletal muscle, liver ...
Rajendra Singh Jain, Arti Gupta, Pankaj Kumar Gupta, Rakesh Agrawal   +3 more
doaj   +1 more source

Analysis on clinical phenotype and gene mutation of progressive myoclonic epilepsy: one case report

Chinese Journal of Contemporary Neurology and Neurosurgery, 2018
Objective To investigate the features of clinical phenotype and gene mutation of progressive myoclonic epilepsy (PME). Methods and Results The main clinical features of a 43-year-old man were photosensitive seizures, progressive cerebellar ataxia and ...
Xing-wang SONG, Yu-qing GUAN, Qian-yi WU, Yong-hong YI   +3 more
doaj   +1 more source

Familial Cortical Myoclonic Tremor with Epilepsy and Cerebellar Changes: Description of a New Pathology Case and Review of the Literature

Tremor and Other Hyperkinetic Movements, 2012
Background: Over 60 Asian and European families with cortical myoclonic tremor and epilepsy have been reported under various names. Cerebellar changes may be part of the syndrome.
Sarvi Sharifi, Eleonora Aronica, Johannes H. T. M. Koelman, Marina A. J. Tijssen, Anne-Fleur van Rootselaar   +4 more
doaj   +1 more source

Comorbid seizure reduction after pallidothalamic tractotomy for movement disorders: Revival of Jinnai’s Forel‐H‐tomy

Epilepsia Open, 2021
Forel‐H‐tomy for intractable epilepsy was introduced by Dennosuke Jinnai in the 1960s. Recently, Forel‐H‐tomy was renamed to “pallidothalamic tractotomy” and revived for the treatment of Parkinson's disease and dystonia. Two of our patients with movement
Shiro Horisawa, Satoru Miyao, Tomokatsu Hori, Kotaro Kohara, Takakazu Kawamata, Takaomi Taira   +5 more
doaj   +1 more source

T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy

Annals of Neurology, EarlyView.
Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes, Lukas Henning, Karen M. J. van Loo, Rainer Surges, Susanne Schoch, Albert J. Becker, Julika Pitsch   +6 more
wiley   +1 more source

Evaluating discrepancies between high‐yield neuroscience conditions in preclerkship medical education and national clinical incidence

Anatomical Sciences Education, EarlyView.
Abstract Medical education must balance foundational science with clinical relevance. Increasing emphasis on standardized assessments has led to prioritization of “high‐yield” conditions—those most likely to be assessed. Subsequently, educators and students often prioritize these conditions.
Kathryn Veazey, Oheneba Boadum
wiley   +1 more source