Results 91 to 100 of about 16,534,485 (359)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Experience of starting a Philosophical practice Programs in Knin, Philosophy with Children and Philosophical Café [PDF]
In Medias Res, 2019 During 2018 we started with two programs in Knin. One was a philosophy program with children as part of the project “Reading for Children” and another program of the “Philosophical cafe”.
Spomenka Martić
doaj
Tanzania: In their own words: Poor women and health services. [PDF]
, 2004 "In Their Own Words: Poor Women And Health Services" highlights critical constraints that poor women experience in accessing health services, including the challenges they face and the strategies they use to overcome them. This summary report is meant to
Women's Dignity Project/Utu Mwanamke, (WDP)
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
MODEL FOR THE FORMATION OF A PROJECT TEAM COMPOSITION BASED ON DISCRETE OPTIMIZATION METHODS
Модели, системы, сети в экономике, технике, природе и обществеBackground. The research is devoted to the development of a model for the formation of optimal team composition for projects in general, and for innovative ones in particular, which are the basis of economic progress in the modern information society ...
S.M. Beketov, M.V. Dergachev, S.G. Redko
doaj +1 more source
Treasures of Portuguese archaeology Notes towards a preventive conservation project [PDF]
, 2009 Isabel Tıssot +3 more
openalex +1 more source
Research on Social Engagement with a Rabbitic User Interface [PDF]
, 2009 Companions as interfaces to smart rooms need not only to be easy to interact with, but also to maintain long-term relationships with their users. The FP7-funded project SERA (Social Engagement with Robots and Agents) contributes to knowledge about and ...
Cunningham, Stuart +3 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source