Results 111 to 120 of about 15,819,940 (362)
Aneurysm of the membranous septum projecting into the right atrium [PDF]
, 1912 Franklin P. Mall
openalex +1 more source
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Projective differential geometry of curved surfaces [PDF]
, 1907 E. J. Wilczynski
openalex +1 more source
A needs and resource assessment approach to developing a comprehensive dental plan for Boston's Head Start program [PDF]
, 1979 Thesis (M.Sc.)--Boston University, Henry M. Goldman School of Graduate Dentistry, 1979 (Dental Public Health).Includes bibliographical references: (leaves 49-50)
Project Head Start (US) +1 more
core
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Some aspects of the project activity of philologists in the continuous education system
Journal of Education, Health and Sport, 2018 The article is devoted to a detailed analysis of pedagogical design and development of basic principles of its implementation in the educational process, as well as the characteristics of the main subjects of pedagogical design.
Olga Strelnyk
doaj
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source