Results 131 to 140 of about 16,534,485 (359)
IMLS PLACE Grant: Campus Journal Press Release [PDF]
, 2013 Campus Journal press release describing the PLACE (Position-based Location Archive Coordinate Explorer) project that is funded by the Institute for Museum and Library Services.
PLACE Project Group
core +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Towards the improvement of project team performance based on large language models
Радіоелектронні і комп'ютерні системиThe subject of the study is a method for identifying poor quality project sprint task descriptions to improve team performance and reduce project risks.
Mykyta Rohovyi, Marina Grinchenko
doaj +1 more source
Characterization of Alaskan Hot-Mix Asphalt containing Reclaimed Asphalt Pavement Material [PDF]
, 2016 In order to properly characterize Alaskan HMA materials containing RAP, this study evaluated properties of 3 asphalt binders typically used in Alaska, PG 52-28, PG 52-40, and PG 58-34, and 11 HMA mixtures containing up to 35% RAP that were either ...
Li, Lin, Liu, Jenny, Zhao, Sheng
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
, 2016 This workshop provides a sound foundation in project planning and development. It is aimed primarily at those people who are relatively new to planning language projects.
Florey, Margaret
core
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source