Results 151 to 160 of about 15,819,940 (362)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

25 million people internally displaced by violence worldwide [PDF]

Forced Migration Review, 2004
Global IDP Project
doaj  

Book Review: Jacob Steiner's Vorlesungen über synthetische Geometrie. Zweiter Theil: Die Theorie der Kegelschnitte gestützt auf projective Eigenschaften [PDF]

, 1899
Isabel Maddison
openalex   +1 more source

Travel Disruption: Three Case Studies [PDF]

This report draws together the findings of three studies of travel disruption and its impacts on travellers: the volcanic ash cloud which disrupted aviation in Europe in 2010, the loss of road bridges between November 2009 and April 2010 at Workington ...
Disruption Project, Guiver, Jo W
core  

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Atolls visited during the first year of the Pacific Islands Rat Ecology Project [PDF]

, 1957
Joe T. Marshall
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

On Certain Projective Generalizations of Metric Theorems, and the Curves of Darboux and Segre

, 1918
Gabriel M. Green
openalex   +1 more source

On a Certain Class of Self-Projective Surfaces [PDF]

, 1913
E. J. Wilczynski
openalex   +1 more source

Parole Preparation Project Publication [PDF]

, 2020
Parole Preparation Project
core   +1 more source