Results 91 to 100 of about 20,529,932 (305)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Естетика і етика педагогічної діїThe article discusses the methodological and practical aspects of preparing future educators for professional activities in inclusive education using project-based technologies.
Л. Шевченко, М. Сорочан
doaj +1 more source
International Journal of Behavioral Nutrition and Physical Activity, 2011 BackgroundThe assessment of physical activity is an essential part of understanding patterns and influences of behaviour, designing interventions, and undertaking population surveillance and monitoring, but it is particularly problematic when using self ...
S. Biddle +3 more
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
RESCON: Educational project scheduling software. [PDF]
In this article we discuss a freely downloadable educational software tool for illustrating project scheduling and project management concepts. The tool features exact and heuristic scheduling procedures and visualizes project networks, project schedules,
Deblaere, Filip +2 more
core
Communication in the classroom: Practice and reflection of a mathematics teacher [PDF]
, 2008 This paper discusses the conceptions, practices and reflections about practices of a mathematics teacher, Maria, with respect to classroom communication and their change during the activity of a collaborative project involving a researcher and two other
Martinho, Maria Helena +1 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Library purchasing consortia: their activity and effect on the marketplace [PDF]
, 2000 This chapter is based on a survey undertaken for a BLRIC/LIC-funded research project (RIC/G/403). It describes the models of operation of purchasing consortia in three library sectors (health, higher education and public libraries) and discusses present
Ball, David, Pye, Jo
core
ISPRS Int. J. Geo Inf., 2012 The OpenStreetMap (OSM) project, founded in 2004, has gathered an exceptional amount of interest in recent years and counts as one of the most impressive sources of Volunteered Geographic Information (VGI) on the Internet.
Pascal Neis, A. Zipf
semanticscholar +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source