Results 101 to 110 of about 20,529,932 (305)

Introducing and Implementing HIV Self-Testing in Côte d'Ivoire, Mali, and Senegal: What Can We Learn From ATLAS Project Activity Reports in the Context of the COVID-19 Crisis? [PDF]

Front Public Health, 2021
Kra AK, Colin G, Diop PM, Fotso AS, Rouveau N, Hervé KK, Geoffroy O, Diallo B, Kabemba OK, Dieng B, Diallo S, Vautier A, Larmarange J.   +12 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Global Entrepreneurship Monitor Scotland 2011 [PDF]

, 2012
GEM is a major research project aimed at describing and analysing entrepreneurial processes within a wide range of countries. GEM has three main objectives: To measure differences in entrepreneurial attitudes, activity and aspirations among economies. To
Levie, Jonathan
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

THE DEVELOPMENT OF THE THEORY AND PRACTICE OF PROJECT MANAGEMENT: THE ROLE OF THE SCIENTIFIC SCHOOL OF THE STATE UNIVERSITY OF MANAGEMENT (PART 2)

Вестник университета, 2019
This article is a continuation of the publication of the results of the study of the evolution of project management as a special type of management activity.
G. Ya. Soroko, I. Z. Kogotkova
doaj   +1 more source

ОСОБЕННОСТИ ОРГАНИЗАЦИИ ПРОЕКТНОЙ ДЕЯТЕЛЬНОСТИ ОБУЧАЮЩИХСЯ НАЧАЛЬНЫХ КЛАССОВ

Научно-педагогическое обозрение, 2020
Рассматривается вопрос организации проектной деятельности в начальной школе как личностно ориентированной технологии, объединяющей в себе различные подходы, методы, методики.
Кондакова Ирина Владимировна, Долгошеева Елена Владимировна, Корякина Галина Александровна   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

ORGANIZATIONAL AND PEDAGOGICAL CONDITIONS FOR FORMING THE READINESS OF FUTURE TEACHERS FOR PROJECT ACTIVITIES IN THE CONTEXT OF DIGITALIZATION OF EDUCATION

Вестник Мининского университета, 2018
Introduction: In the article the organizational and pedagogical conditions of readiness of future teachers for the project activity in conditions of digitalization of education are analyzed.
E. K. Samerhanova, Z. U. Imzharova
doaj   +1 more source

Use of project activity in integrated teaching of the English and Kazakh languages to students of economics faculty [PDF]

In the work we gave the definition of the project activity and considered the use of the project activity in the integrated teaching of the English and Kazakh languages to students of the faculty of economics.Project, integrated teaching, methodology ...
Moldakhmetova, Gulnara
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source