Results 111 to 120 of about 20,529,932 (305)

Giftedness as a Pedagogical Problem

Развитие образования, 2020
The difference between the concepts of ability and giftedness in the context of a competency approach to education, when competence and expert knowledge are distinguished is clarified in the article.
Vladimir A. Tomilov, Margarita M. Krivenko   +1 more
doaj   +1 more source

Mid-term report for the CORE Organic II funded project. “Innovative cropping Practices to increase soil health of organic fruit tree orchards” BIO-INCROP [PDF]

, 2013
Activities performed in the first part of BIO-INCROP project concern five of the eight main objectives fixed in the project proposal. They are: Evaluation of soil borne pest and pathogens involved in replant disease Role of rhizospheric bacterial ...
Baab, G., Canet, R., Franke-Whittle, I., Kaymak, S., Kelderer, M., Manici, L.M., Naef, A., Rühmer, T.   +7 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Russian Institute for Advanced Study as a New Form of Training of Highly Trained Teaching Staff

Интеграция образования, 2017
Introduction: the aim of the paper is the analysis of role and capabilities of the Russian Institute for Advanced Study under Moscow State Pedagogical University in preparation of the top qualification scientific and teaching staff, possessing not only ...
Vsevolod V. Andreev, Rustem Ya. Gibadulin, Georgi Prodanov, Renad I. Zhdanov   +3 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

On the use of schedule risk analysis for project management [PDF]

, 2015
The purpose of this paper is to give an overview on the existing literature and recent developments on the research on Schedule Risk Analysis (SRA) in Project Management (PM) to measure the sensitivity of activities and resources in the project network ...
Vanhoucke, Mario
core  

Chromospheric CaII Emission in Nearby F, G, K, and M stars

, 2004
We present chromospheric CaII activity measurements, rotation periods and ages for ~1200 F-, G-, K-, and M- type main-sequence stars from ~18,000 archival spectra taken at Keck and Lick Observatories as a part of the California and Carnegie Planet Search
G. W. Marcy, J. T. Wright, Middelkoop F., Perryman M. A. C., R. Paul Butler, S. S. Vogt, Santos N. C., Vogt S. S.   +7 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Marathon “Twelve Collegia”: Developing agency and university values [PDF]

Известия Саратовского университета. Новая серия: Акмеология образования. Психология развития
The relevance of the study stems from the tension between society’s demand for specialists in secondary vocational education and the narrowing higher educational prospects for gifted middle school students (grades 5–8).
Азбель, Анастасия Анатольевна, Pekoun, Margarita E.   +1 more
doaj   +1 more source