Results 91 to 100 of about 4,645,684 (346)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Commissioning and co‐production in health and care services in the United Kingdom and Ireland: An exploratory literature review

Health Expectations
Introduction This exploratory literature review seeks to examine the literature around commissioning processes in the co‐production of health and care services, focusing on two questions: How do health and care commissioning processes facilitate and/or ...
Rebecca J. Scott, Elspeth Mathie, Hannah J. H. Newman, Kathryn Almack, Louca‐Mai Brady   +4 more
doaj   +1 more source

The other GMP: good manufacturing practice and its importance in the validation of constructed pharmaceutical facilities [PDF]

, 2005
The work reported is part of an ongoing PhD study prompted by the particular difficulties encountered when two very different quality cultures interact (in this case Pharmaceutical industry clients and Construction industry providers).
Edge, Jerry, Greenwood, David, Render, Neil   +2 more
core  

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Shielding and Activation Analyses for BTF Facility at SNS

EPJ Web of Conferences, 2017
The beam test facility (BTF), which simulates front end of the Spallation Neutron Source (SNS), has been built at the SNS, and is preparing for commissioning. The BTF has been assembled and will operate in one of service buildings at the site.
Popova Irina, Gallmeier Franz X.
doaj   +1 more source

Overview of the IFMIF/EVEDA project

, 2017
IFMIF, the International Fusion Materials Irradiation Facility, is presently in its engineering validation and engineering design activities (EVEDA) phase under the Broader Approach Agreement.
J. Knaster, P. Garin, H. Matsumoto, Yoshikazu Okumura, M. Sugimoto, F. Arbeiter, Philippe Cara, S. Chel, A. Facco, P. Favuzza, T. Furukawa, R. Heidinger, Ángel Ibarra, T. Kanemura, A. Kasugai, H. Kondo, V. Massaut, J. Mollá, G. Miccichè, S. Ohira, Keishi Sakamoto, T. Yokomine, E. Wakai   +22 more
semanticscholar   +1 more source

Integrated children’s services: conformity, diversity and managing the market: sharing our experience, practitioner-led research 2008-2009 [PDF]

, 2009
This report is part of CWDC’s Practitioner-Led Research (PLR) programme. Now in its third year, the programme gives practitioners the opportunity to explore, describe and evaluate ways in which services are currently being delivered within the children ...

core  

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

The FARCOS project. First characterization of CsI(Tl) crystals of the FARCOS array using charged particle beams at LNS

EPJ Web of Conferences, 2014
The construction of a new array to study femtoscopy and multi-particle correlations in heavy ion collisions at intermediate energies (E=20-1000 AMeV) has been started at the INFN.
Quattrocchi L., Acosta L., De Filippo E., Minniti T., Pagano E. V., Russotto P., Trifirò A., Verde G., Amorini F., Anzalone A., Auditore L., Boiano C., Cardella G., Castoldi A., Francalanza L., Gianì R., Guazzoni C., Lanzalone G., Lombardo I., Morgana E., Norella S., Pagano A., Papa M., Pirrone S., Politi G., Riccio F., Rizzo F., Trimarchi M., Zambon P.   +28 more
doaj   +1 more source

Assessment of Energy Credits in LEED-Certified Buildings Based on Certification Levels and Project Ownership

Buildings, 2018
Compared to other categories, the Energy and Atmosphere category contributes the most to the maximum obtainable points in the Leadership in Energy and Environmental Design (LEED) certification system. The objective of the study was to identify the extent
Asli Pelin Gurgun, David Arditi
doaj   +1 more source