Results 91 to 100 of about 167,409 (351)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Key Points in Line Splitting for Hangzhou Metro Line 1 Linping Branch

open access: yesChengshi guidao jiaotong yanjiu
ObjectiveThe splitting and renovation construction of metro operating lines is a highly complex task that involves multiple professional disciplines and challenges related to compatibility between new and existing systems. Such projects are characterized
Zhiming SUN
doaj   +1 more source

An evaluation of approaches to commissioning young people’s services [PDF]

open access: yes, 2011
"This small-scale survey examines approaches to the commissioning of services for young people in 12 local authority areas and reports on the experience of national organisations involved in this work" - front ...

core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Instrumentation status of the low-b magnet systems at the Large Hadron Collider (LHC)

open access: yes, 2011
The low-beta magnet systems are located in the Large Hadron Collider (LHC) insertion regions around the four interaction points. They are the key elements in the beams focusing/defocusing process allowing proton collisions at luminosity up to 10**34/cm ...
/CERN   +6 more
core   +1 more source

Information Management within the LHC Hardware Commissioning Project [PDF]

open access: yes, 2009
The core task of the commissioning of the LHC technical systems was the individual test of the 1572 superconducting circuits of the collider, the powering tests.
Bellesia, B   +11 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

The New Perspective of IT Project Management

open access: yesEIRP Proceedings, 2021
Carrying out an IT project is a complex and long-lasting activity, which involves large material, human and time resources. By analogy, the realization of an IT project can be very similar to the achievement of an investment objective.
Cătălina Sitnikov   +3 more
doaj  

THE SECRET SOUTH AFRICAN PROJECT TEAM: BUILDING STRIKE CRAFT IN ISRAEL, 1975-79

open access: yesScientia Militaria, 2012
Though the history of the South African Navy (SAN) only dates back to 1922, for most of its history it depended on Britain for warships. The British Royal Navy on the other hand had an unbroken involvement with maritime defence along the South African ...
Thean Potgieter
doaj   +1 more source

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