Results 101 to 110 of about 4,645,684 (346)

Advances of the FRIB project

open access: yesInternational Journal of Modern Physics E, 2019
The Facility for Rare Isotope Beams (FRIB) Project has entered the phase of beam commissioning starting from the room-temperature front end and the superconducting linac segment of first 15 cryomodules.
J. Wei   +46 more
semanticscholar   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

The New Perspective of IT Project Management

open access: yesEIRP Proceedings, 2021
Carrying out an IT project is a complex and long-lasting activity, which involves large material, human and time resources. By analogy, the realization of an IT project can be very similar to the achievement of an investment objective.
Cătălina Sitnikov   +3 more
doaj  

Ring Laser gyroscopes and Gravitational waves research [PDF]

open access: yesEPJ Web of Conferences
The INFN research for the development of top sensitivity ring laser gyroscope began about 15 years ago. At that time the aim was to develop top sensitivity tilt-meter for the Virgo suspensions, and the CSN5 in 2009 has financed a first project to learn ...
Beverini Nicolo   +6 more
doaj   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Instrumentation status of the low-b magnet systems at the Large Hadron Collider (LHC)

open access: yes, 2011
The low-beta magnet systems are located in the Large Hadron Collider (LHC) insertion regions around the four interaction points. They are the key elements in the beams focusing/defocusing process allowing proton collisions at luminosity up to 10**34/cm ...
/CERN   +6 more
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

THE SECRET SOUTH AFRICAN PROJECT TEAM: BUILDING STRIKE CRAFT IN ISRAEL, 1975-79

open access: yesScientia Militaria, 2012
Though the history of the South African Navy (SAN) only dates back to 1922, for most of its history it depended on Britain for warships. The British Royal Navy on the other hand had an unbroken involvement with maritime defence along the South African ...
Thean Potgieter
doaj   +1 more source

Multi-objective optimization of discrete time–cost tradeoff problem in project networks using non-dominated sorting genetic algorithm

open access: yes, 2016
The time–cost tradeoff problem is one of the most important and applicable problems in project scheduling area. There are many factors that force the mangers to crash the time.
M. Shahriari
semanticscholar   +1 more source

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