Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
When the Project Ends and Operations Begin: Ensuring Safety During Commissioning Through Boundary Work [PDF]
, 2022 Anne Russel, Stéphanie Tillement
openalex +1 more source
Molecular Oncology, EarlyView.We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
Using a Community Engagement approach to ensure equality of access, experience and outcome from the IAPT programme in the North West of England [PDF]
, 2009 This report summarises the findings of seven equality impact assessments carried out by seven community organisations across the North West of England examining the equality issues for specific communities in connection with the roll out of the Improving
Ahmed, Nadia, Buffin, Jez, Singh, M
core
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
MOTYGINSKAYA HYDROPOWER PLANT IMPACT ON DOWNSTREAM ICE PROCESSES
RUDN Journal of Engineering Research, 2015 The article seeks to conduct research on the possible consequences on existing regimes of the Angara River after the construction of Motyginskaya hydropower plant.
A V Shtil, N K Ponomarev, I I Gritsuk
doaj
Fulfilling Lives: Supporting people with multiple needs, Evaluation Report, Year 1 [PDF]
, 2015 This report is prepared for the Big Lottery Fund (the Fund) by the national evaluationteam and provides emerging findings and lessons learned from the first year of thenational evaluation of the Fulfilling Lives: Supporting people with multiple ...
Hayley Lamb +4 more
core
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Commission on Spin, Charge and Momentum Density. Project No. 1. Standardization of Compton profile measurements – The Compton profile of water [PDF]
, 1976 Brian Williams
openalex +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source