Results 61 to 70 of about 4,645,684 (346)

Improving the capabilities of NHS organisations to use evidence: a qualitative study of redesign projects in Clinical Commissioning Groups

Health Services and Delivery Research, 2017
Background: Innovation driven by authoritative evidence is critical to the survival of England’s NHS. Clinical Commissioning Groups (CCGs) are central in NHS efforts to do more with less. Although decisions should be based on the ‘best available evidence’
Jacqueline Swan, Emmanouil Gkeredakis, Rachel M Manning, Davide Nicolini, David Sharp, John Powell   +5 more
doaj   +1 more source

Patient-level data linkage across ambulance services and acute trusts: assessing the potential for improving patient care

International Journal of Population Data Science, 2017
Objectives The potential of linked healthcare data to support improvements to the care quality, efficiency and service planning is recognised by the Department of Health and NHS England.
Sophie Clark, Michael Damiani, Holly Dorning, Mary Halter, Alison Porter   +4 more
doaj   +1 more source

ReseArch with Patient and Public invOlvement: a RealisT evaluation - the RAPPORT study [PDF]

, 2015
Background Patient and public involvement (PPI) is a prerequisite for many funding bodies and NHS research ethics approval. PPI in research is defined as research carried out with or by the public rather than to, about or for them.
Abbott, Abma, All-Party Parliamentary Group, Andejeski, Armes, Astbury, Badger, Baggott, Baggott, Barber, Barber, Barber, Barbour, Barnes, Barnes, Barnes, Barnes, Barnes, Barnes, Barnes, Barnes, Batsch, Baxter, Ben-Ari, Beresford, Bhaskar, Boivin, Boote, Boote, Boote, Boote, Brannen, Brett, Brett, Brett, British Paediatric Surveillance Unit, Broerse, Burrus, Cairncross, Caldon, Callard, Caron-Flinterman, Carter, Chalmers, Clark, Clavier, Collaboration for Leadership in Applied Health Research and Care, Collier, Connelly, Connelly, Consumers Health Forum of Australia, Cotterell, Cotterell, Cystic Fibrosis Trust, Davis, Davis, Delanty, Delbanco, Department of Health, Department of Health, Department of Health, Department of Health, Department of Health, Department of Health, Department of Health, Department of Health, Department of Health, Dewar, Edwards, Elberse, Entwistle, Entwistle, Evans, Expert Patients Programme, Exworthy, Fairbrother, Faulkner, Fiss, Forbat, Forbes, Fulop, Gibson, Goodman, Goodman, Gradinger, Great Britain, Greene, Guarino, Habermas, Habermas, Habermas, Hartley, Hawe, Hayes, Held, Hewitt, Hewlett, Higher Education Funding Council for England, HM Government, HM Government, Hofmann, Howe, Howe, Hunn, Hunt, Iliffe, INVOLVE, INVOLVE, Ives, Jagosh, Jagosh, Jordan, Kontos, Koops, Kreindler, Kreis, Krieger, Langston, Lasker, Lindenmeyer, Lupton, Macaulay, Marchal, Marinetto, Martin, Martin, Mathie, Matthews, May, May, May, May, McCormick, McDonnell, McGrath, McKevitt, McKevitt, McNichol, Medical Research Council, Merton, Meyer, Middleton, Miller, Milton, Minogue, Morrow, Nathan, National Cancer Research Institute, National Institute of Health Research, National Institutes of Health, National Voices, Ocloo, Oliver, Oliver, Oliver, Oliver, O’Cathain, O’Donnell, Palmer, Parkes, Paterson, Patient and Public Involvement Solutions, Pattengill-Semmens, Pawson, Pawson, Pawson, Peckham, Philpot, PiiAF Study Group, Pitt, Prior, Purttell, Renedo, Research Design Service London, Rhodes, Roderick, Royal College of Psychiatry, Royle, Rycroft-Malone, Rycroft-Malone, Savage, Schierhout, Schneider, Schwappach, Scott, Shippee, Shirk, Smith, Snape, Staley, Staley, Staley, Staley, Staniszewska, Staniszewska, Staniszewska, Staniszewska, Staniszewska, Stevens, Strauss, Sutton, Telford, Telford, Terry, Thompson, Thompson, Thompson, Titmuss, Tolson, Tritter, Truman, Vale, van Bekkum, Walker, Wand, Ward, Williams, Williams, Williamson, Wilson, Wilson, Wilson, Wilson, World Health Organization, Wright, Yin   +225 more
core   +4 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Mapping of Hydrogen Fuel Quality in Europe

Frontiers in Energy Research, 2020
As part of FCH-JU funded HyCoRA project running from 2014 to 2017, 28 gaseous and 13 particulate samples were collected from hydrogen refueling stations in Europe.
Thor A. Aarhaug, Ole S. Kjos, Alain Ferber, Jong Pyong Hsu, Thomas Bacquart   +4 more
doaj   +1 more source

A cost and pipeline trade-off in a transportation problem [PDF]

Yugoslav Journal of Operations Research, 2013
The present paper deals with a trade off between cost and pipeline at a given time in a transportation problem. The time lag between commissioning a project and the time when the last consignment of goods reaches the project site is an important ...
Sharma Vikas, Malhotra Rita, Verma Vanita   +2 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

SwissFEL: The Swiss X-ray Free Electron Laser

Applied Sciences, 2017
The SwissFEL X-ray Free Electron Laser (XFEL) facility started construction at the Paul Scherrer Institute (Villigen, Switzerland) in 2013 and will be ready to accept its first users in 2018 on the Aramis hard X-ray branch.
Christopher J. Milne, Thomas Schietinger, Masamitsu Aiba, Arturo Alarcon, Jürgen Alex, Alexander Anghel, Vladimir Arsov, Carl Beard, Paul Beaud, Simona Bettoni, Markus Bopp, Helge Brands, Manuel Brönnimann, Ingo Brunnenkant, Marco Calvi, Alessandro Citterio, Paolo Craievich, Marta Csatari Divall, Mark Dällenbach, Michael D’Amico, Andreas Dax, Yunpei Deng, Alexander Dietrich, Roberto Dinapoli, Edwin Divall, Sladana Dordevic, Simon Ebner, Christian Erny, Hansrudolf Fitze, Uwe Flechsig, Rolf Follath, Franziska Frei, Florian Gärtner, Romain Ganter, Terence Garvey, Zheqiao Geng, Ishkhan Gorgisyan, Christopher Gough, Andreas Hauff, Christoph P. Hauri, Nicole Hiller, Tadej Humar, Stephan Hunziker, Gerhard Ingold, Rasmus Ischebeck, Markus Janousch, Pavle Juranić, Mario Jurcevic, Maik Kaiser, Babak Kalantari, Roger Kalt, Boris Keil, Christoph Kittel, Gregor Knopp, Waldemar Koprek, Henrik T. Lemke, Thomas Lippuner, Daniel Llorente Sancho, Florian Löhl, Carlos Lopez-Cuenca, Fabian Märki, Fabio Marcellini, Goran Marinkovic, Isabelle Martiel, Ralf Menzel, Aldo Mozzanica, Karol Nass, Gian Luca Orlandi, Cigdem Ozkan Loch, Ezequiel Panepucci, Martin Paraliev, Bruce Patterson, Bill Pedrini, Marco Pedrozzi, Patrick Pollet, Claude Pradervand, Eduard Prat, Peter Radi, Jean-Yves Raguin, Sophie Redford, Jens Rehanek, Julien Réhault, Sven Reiche, Matthias Ringele, Jochen Rittmann, Leonid Rivkin, Albert Romann, Marie Ruat, Christian Ruder, Leonardo Sala, Lionel Schebacher, Thomas Schilcher, Volker Schlott, Thomas Schmidt, Bernd Schmitt, Xintian Shi, Markus Stadler, Lukas Stingelin, Werner Sturzenegger, Jakub Szlachetko, Dhanya Thattil, Daniel M. Treyer, Alexandre Trisorio, Wolfgang Tron, Seraphin Vetter, Carlo Vicario, Didier Voulot, Meitian Wang, Thierry Zamofing, Christof Zellweger, Riccardo Zennaro, Elke Zimoch, Rafael Abela, Luc Patthey, Hans-Heinrich Braun   +114 more
doaj   +1 more source

UC Berkeley's Cory Hall: Evaluation of Challenges and Potential Applications of Building-to-Grid Implementation [PDF]

, 2010
From September 2009 through June 2010, a team of researchers developed, installed, and tested instrumentation on the energy flows in Cory Hall on the UC Berkeley campus to create a Building-to-Grid testbed.
Peffer, Therese
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source