Results 71 to 80 of about 4,645,684 (346)

Evidence synthesis on the occurrence, causes, consequences, prevention and management of bullying and harassment behaviours to inform decision making in the NHS [PDF]

, 2013
Background Workplace bullying is a persistent problem in the NHS with negative implications for individuals, teams, and organisations. Bullying is a complex phenomenon and there is a lack of evidence on the best approaches to manage the problem ...
Burford, Bryan, Carter, Madeline, Cooke, A., Crampton, Paul, Howse, Jenny, Illing, Jan, Morrow, Gill, Thompson, Neill   +7 more
core  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Preventing Domestic Abuse for Children and Young People (PEACH): A Mixed Knowledge Scoping Review [PDF]

, 2015
Background: A range of interventions that aim to prevent domestic abuse has been developed for children and young people in the general population. While these have been widely implemented, few have been rigorously evaluated. This study aimed to discover
Bailey, Sue, Downe, Soo, Ellis, Jane, Farrelly, Nicola, Hollinghurst, Sandra, Stanley, Nicky   +5 more
core   +2 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

BESS Project Commissioning.

Proposed for presentation at the Resilience Week 2021 held October 18-21, 2021 in Washington, District of Columbia US, 2021
W. Clark, Daniel R. Borneo
semanticscholar   +1 more source

Supporting arts and enterprise skills in communities through creative engagement with the local area [PDF]

, 2011
The project proposes a framework and methodology of artistic and creative social intervention that empowers and supports engagement with communities of young people affected by change in their local environment.
Haywood, P, Ingleson, SJ
core   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Commission problems and countermeasures of integrated membrane technology in boiler make-up water system of a power plant

Gongye shui chuli
Based on the technical renovation project of boiler make-up water system in a power plant in North China，the design characteristics and operation mode of ultrafiltration-first stage reverse osmosis-second stage reverse osmosis-electrodeionization（EDI ...
ZHANG Kai, CHEN Yuqiang, CHEN Yang, LI Xiaojun, WANG Niuwang, LIU Guidong, HU Mingrui   +6 more
doaj   +1 more source

Commissioning of the JT-60SA helium refrigerator

, 2017
The JT-60SA project will use superconducting magnets to confine the plasma and achieve a plasma current with a typical flat top duration of 100 second in purely inductive mode.
K. Kamiya, K. Natsume, K. Ohtsu, M. Oishi, Atsushi Honda, Y. Kashiwa, K. Kizu, Y. Koide, C. Hoa, Frederic Michel, P. Roussel, V. Lamaison, F. Bonne, E. Dipietro, A. Cardella, M. Wanner, J. Legrand, V. Pudys, B. Langevin   +18 more
semanticscholar   +1 more source

Preparatory study for the revaluation of the EQ-5D tariff: methodology report. [PDF]

, 2014
BACKGROUND: EQ-5D is a widely used generic measure of health with a 'tariff', or preference weights, obtained from the general population, using time trade-off (TTO).
Bansback, Nick, Brazier, John, Buckingham, Ken, Cairns, John, Devlin, Nancy, Dolan, Paul, Hole, Arne Risa, Kavetsos, Georgios, Longworth, Louise, Mulhern, Brendan, Rowen, Donna, Tsuchiya, Aki   +11 more
core   +3 more sources