Results 81 to 90 of about 4,645,684 (346)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

CERN ELENA project progress report

EPJ Web of Conferences, 2015
The Extra Low Energy Antiproton ring (ELENA) is a CERN project aiming at constructing a 30 m circumference synchrotron to further decelerate antiprotons from the Antiproton Decelerator (AD) from 5.3 MeV to 100 keV.
Bartmann Wolfgang, Belochitskii Pavel, Breuker Horst, Butin François, Carli C., Eriksson Tommy, Oelert Walter, Maury Stephan, Pasinelli Sergio, Tranquille Gerard   +9 more
doaj   +2 more sources

Research on Engineering Acceptance Measures and Safety Evaluation Schemes of City Railway New Projects in Shanghai

Chengshi guidao jiaotong yanjiu
Objective Several projects of city railway in Shanghai are currently under construction. However, there are no well-defined engineering acceptance and safety evaluation management measures for new city railway projects at the moment.
Zhiping LIU, Yang LIU
doaj   +1 more source

Information Management within the LHC Hardware Commissioning Project [PDF]

, 2009
The core task of the commissioning of the LHC technical systems was the individual test of the 1572 superconducting circuits of the collider, the powering tests.
Bellesia, B, Fernández-Robles, C, Koratzinos, M, Marqueta Barbero, A, Pojer, M, Saban, R, Schmidt, R, Solfaroli Camilloci, M, Szkutnik, J, Vergara Fernández, A, Wenninger, J, Zerlauth, M   +11 more
core  

The KELT-South Telescope

, 2012
The Kilodegree Extremely Little Telescope (KELT) project is a survey for new transiting planets around bright stars. KELT-South is a small-aperture, wide-field automated telescope located at Sutherland, South Africa.
David James, Erasmus D. A., Høg E., Joshua Pepper, Keivan Stassun, Pepper J., Robert Siverd, Rudolf B. Kuhn, Zacharias N.   +8 more
core   +1 more source

Changing practice in dementia care in the community: developing and testing evidence-based interventions, from timely diagnosis to end of life (EVIDEM) [PDF]

, 2015
Background Dementia has an enormous impact on the lives of individuals and families, and on health and social services, and this will increase as the population ages.
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core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Cybernetic Model Design for the Qualification of Pharmaceutical Facilities

Applied Sciences
In this paper, an integrated cybernetic model for managing qualification activities when commissioning pharmaceutical facilities is created, focusing on defining critical factors that provide all the prerequisites for the start of the production process.
Ilija Tabasevic, Dragan D. Milanovic, Vesna Spasojevic Brkic, Mirjana Misita, Aleksandar Zunjic   +4 more
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Sub-barrier fusion cross section measurements with STELLA

EPJ Web of Conferences, 2017
The experimental setup STELLA (STELlar LAboratory) is designed for the measurement of deep sub-barrier light heavy ion fusion cross sections. For background suppression the γ-particle coincidence technique is used.
Heine M., Courtin S., Fruet G., Jenkins D.G., Montanari D., Adsley P., Beck C., Della Negra S., Dené P., Haas F., Hammache F., Heitz G., Kirsebom O.S., Krauth M., Lesrel J., Meyer A., Morris L., Regan P.H., Richer M., Rudigier M., de Séréville N., Stodel C.   +21 more
doaj   +1 more source