Results 131 to 140 of about 21,342,775 (312)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Mosquito Control Commission, operating manual
, 1935 This item is the operating manual of the Mosquito Control Commission for the State of Delaware. Its creation in August of 1935 is attributed to Pleasant McCarty.
Mosquito Control Commission
core +2 more sources
Mini project : stepper motor control : document transcript
, 2010 This is Mini Project documentation about stepper motor control. It is part of the 2009/10 BEng in Digital Systems and Computer Engineering (course number 2ELE0065) from the University of Hertfordshire.
University of Hertfordshire, School of Electronic Communications and Electrical Engineering
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Mini project : stepper motor control : presentation transcript
, 2010 This is a Mini Project presentation about stepper motor control. It is part of the 2009/10 BEng in Digital Systems and Computer Engineering (course number 2ELE0065) from the University of Hertfordshire.
University of Hertfordshire, School of Electronic Communications and Electrical Engineering
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Status reports to the process simulation and control project advisory committee
, 1993 "April 26, 1993."MAPPS development: project 3576 / Gary Jones ; Simulation of dynamics and control of a two-ply paper machine / Gary L. Jones, Steven A. Koepke ; Prediction of paper color: a process simulation approach / Gary L. Jones, Mayank Chaturvedi,
Chaturvedi, Mayank +3 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Malaria JournalAntimalarial drug resistance leads to increased treatment failures, prolonged illness, and increased mortality. The World Health Organization (WHO) recommends malaria-endemic countries regularly (ideally biennially) assess the efficacy of commonly used ...
Irene Cavros +19 more
doaj +1 more source