Results 61 to 70 of about 7,578,805 (306)

One-Year Effects of Project EX in Spain: A Classroom-Based Smoking Prevention and Cessation Intervention Program. [PDF]

open access: yes, 2015
BackgroundTobacco use prevalence rates are high among Spanish adolescents. Programming to counteract tobacco use is needed.Methods and findingsThe current study provides a one-year follow-up outcome evaluation of Project EX, an eight-session classroom ...
Espada, José P   +4 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Development of a MATLAB/Simulink - Arduino environment for experimental practices in control engineering teaching [PDF]

open access: yes, 2019
This project presents the steps followed when implementing a platform based on MATLAB/Simulink and Arduino for the restoration of digital control practices. During this project, an Arduino shield has being designed.
Lerma Macaya, Eneko
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Linking young men who have sex with men (YMSM) to STI physicians: a nationwide cross-sectional survey in China

open access: yesBMC Infectious Diseases, 2018
Background Many young men who have sex with men (YMSM) are reluctant to seek health services and trust local physicians. Online information seeking may encourage YMSM to identify and see trustworthy physicians, obtain sexual health services, and obtain ...
Bolin Cao   +9 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Users' Perceptions of Environmental Control Systems [PDF]

open access: yes, 2009
This paper presents users' perceptions of the benefits and challenges of environmental control systems, the data having been collected as part of a project developing a new speech-driven environmental control system.
Hawley, Mark   +2 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Physical and insecticidal durability of PermaNet® 3.0 and Olyset® plus piperonyl butoxide-synergist insecticide-treated nets in Sierra Leone: results of durability monitoring from 2020 to 2023

open access: yesMalaria Journal
Background The performance of two piperonyl butoxide (PBO-synergist) insecticide-treated net (ITN) brands, PermaNet® 3.0 and Olyset® Plus, were evaluated under field conditions in two neighboring districts in Sierra Leone over 36 months to estimate ...
Raymond Kiprop Sudoi   +22 more
doaj   +1 more source

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