A project-level dataset of Chinese Belt and Road energy investments 2013-2023. [PDF]
Sci DataYin G, Calzadilla A, Bleischwitz R.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Designing a Smart Product-Service System to support digital crowdfunding platforms. [PDF]
Sci RepSalwin M, Waszkiewicz AE.
europepmc +1 more source
The delaying effect of financing constraints on investment [PDF]
We develop a simple model in which a firm considers a number of investment projects. Because of limited financial resources, the firm can undertake at most one project.
Laar,Mindel,van de, Letterie,Wilko
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
From individual burden to social risk pooling: drivers of the declining out-of-pocket health expenditure share in China (2009-2024). [PDF]
Int J Equity HealthQiu T, Shi L, Zhou W, Deng J, Sun G.
europepmc +1 more source
Multiple-bank lending: diversification and free-riding in monitoring [PDF]
This paper analyses banks' choice between lending to firms in exclusive relationships and sharing financing with other banks in a context where both firms and banks are subject to moral hazard problems, and bank monitoring is essential for financing to ...
Carletti, Elena +2 more
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Trends in government and donor funding for vertical and horizontal community health worker programmes in sub-Saharan Africa. [PDF]
BMJ Glob HealthShukla S +10 more
europepmc +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source