Results 91 to 100 of about 5,104,399 (355)
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source
Project risk management for community-based post-disaster housing reconstruction project [PDF]
Indonesia is a highly disaster prone country, particularly to earthquakes. In the last decade, Indonesia has been hit by three large earthquakes; Aceh in December 2004, Yogyakarta in May 2006, and West Sumatra in September 2009.
Amaratunga, Dilanthi+2 more
core
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source
Principles of project management [PDF]
The basic principles of project management as practiced by NASA management personnel are presented. These principles are given as ground rules and guidelines to be used in the performance of research, development, construction or operational ...
core +1 more source
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban+12 more
wiley +1 more source
Managing projects for change: contextualised project management [PDF]
This paper will detail three projects which focussed on enhancing online learning at a large Australian distance education University within a School of Business,School of Health and School of Education. Each project had special funding and took quite distinctive project management approaches, which reflect the desire to embed innovation and ownership ...
Tynan, Belinda+5 more
openaire
PROJECT-BASES RISK MANAGEMENT [PDF]
The project-bases concept is presented. There are defined operations on project-bases. The software developed for project-bases management is analyzed based in its structure and functionality.
Andrei Sandu
core
Is agile project management applicable to construction? [PDF]
This paper briefly summarises the evolution of Agile Project Management (APM) and differentiates it from lean and agile production and ‘leagile’ construction.
Codinhoto, R+3 more
core
Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik+4 more
wiley +1 more source