Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan +46 more
wiley +1 more source
Potential features of building information modeling (BIM) for application of project management knowledge areas in the construction industry. [PDF]
Heliyon, 2023 Raza MS +3 more
europepmc +1 more source
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities
Annals of Clinical and Translational Neurology, EarlyView.Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski +13 more
wiley +1 more source
Project Planning and Control in a Developing Economy: Implementation and Realisation [PDF]
Journal of Design and the Built Environment, 2005 In the competitive and uncertain environment of the construction industry, the ability to deliver end products with the required quality, schedule and budget is vital to the survival of any construction-related firm.
H. Abdul-Rahman +5 more
doaj
Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague +8 more
wiley +1 more source
Introduction of a Single Electronic Health Record for Maternity Units in Ireland: Outline of the Experiences of the Project Management Team. [PDF]
JMIR Form Res, 2023 Sheehan OM +8 more
europepmc +1 more source
Nuclear Energy Fuel Cycle (NEFC) Knowledge Management Project.
, 2022 Janette Meacham
openalex +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Paroxysmal kinesigenic dyskinesia (PKD) is the most common hereditary paroxysmal movement disorder. The PRRT2 gene is the first identified causative gene and accounts for the majority of PKD. In this study, we investigated the pathogenicity of PRRT2 variants in the splice regions. Methods Patients with clinically suspected PKD and no
Jiao‐Jiao Xu +5 more
wiley +1 more source
Data for the project management, life cycle inventory, costings and energy production of a ground-mounted photovoltaic farm in Greece. [PDF]
Data Brief, 2023 Tsinarakis G +3 more
europepmc +1 more source