Results 71 to 80 of about 2,602,400 (347)

Using the PMO to enforce and standardize the attention of software project managers to needs of software project teams

open access: yesInternational Journal of Information Systems and Project Management, 2023
Software project teams (SPTs) are critical stakeholders. Their contribution in successful delivery of software projects is unquestionable. However, the empirical evidence of their importance seems to exist on paper only, as software project managers ...
Robert Hans, Ernest Mnkandla
doaj  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Los Angeles Labor Negotiations Study [PDF]

open access: yes, 2006
[Excerpt] Sjoberg Evashenk Consulting and Cornell University have completed a study of the City of Los Angeles’ labor negotiation policies, processes and practices, under contract with the City Controller’s Office.
Cornell University, School of Industrial and Labor Relations   +1 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Research advances in energy management and harvesting technologies for autonomous profiling floats

open access: yesFrontiers in Marine Science
Autonomous profiling floats, such as the Argo floats, predominantly rely on battery power for their energy supply. However, the limited energy storage capacity of batteries imposes significant constraints on their operational lifespan, observation ...
Yuxia Yu   +7 more
doaj   +1 more source

Exploring lean office in project management by means of a systematic literature review [PDF]

open access: yesInternational Journal of Industrial Engineering and Operations Management
Purpose – This study aims to find the main contributions from lean office (LO) that can be applied to the project management field, correlating these two areas toward an improvement in project management performance.
Edson Oliveira Martins   +1 more
doaj   +1 more source

Research data management for librarians: getting started [PDF]

open access: yes, 2013
Many libraries are keen to take on new roles in providing support for effective research data management (RDM), but lack the necessary skills and resources to do so.
Ball, Joanna
core   +2 more sources

Project management office in non-governmental organizations: an ex post facto study

open access: yes, 2018
Purpose The purpose of this paper is to explore the influence of project management offices (PMO) in non-governmental organizations (NGOs), in fundraising linked to projects, under the theoretical lens of the resource-based view. Design/
A. Lacruz, E. Cunha
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

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